CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044854
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Formin-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 FMNL1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
26SLDLSALKSKAAQKAubiquitination[1, 2, 3]
28DLSALKSKAAQKAPSubiquitination[3]
36AAQKAPSKATLIEANubiquitination[1]
201LDALLEMKSTDRKQTubiquitination[1]
273QDDCMVLKEFLRANSubiquitination[1, 2]
291DKLLADSKTAQEAFEubiquitination[1]
329RFIKAYKKAEQEVEQubiquitination[2]
338EQEVEQWKKEAAAQEubiquitination[2]
377MDLISELKRRQQKEPubiquitination[1, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 488 AA 
Protein Sequence
ELDMSDFEEQ FKTKSQGPSL DLSALKSKAA QKAPSKATLI EANRAKNLAI TLRKGNLGAE 60
RICQAIEAYD LQALGLDFLE LLMRFLPTEY ERSLITRFER EQRPMEELSE EDRFMLCFSR 120
IPRLPERMTT LTFLGNFPDT AQLLMPQLNA IIAASMSIKS SDKLRQILEI VLAFGNYMNS 180
SKRGAAYGFR LQSLDALLEM KSTDRKQTLL HYLVKVIAEK YPQLTGFHSD LHFLDKAGSV 240
SLDSVLADVR SLQRGLELTQ REFVRQDDCM VLKEFLRANS PTMDKLLADS KTAQEAFESV 300
VEYFGENPKT TSPGLFFSLF SRFIKAYKKA EQEVEQWKKE AAAQEAGADT PGKGEPPAPK 360
SPPKARRPQM DLISELKRRQ QKEPLIYESD RDGAIEDIIT GKGLARPWSY PQSVLLCFLL 420
TQCAILWGTG CHTASCYLFC FSFLFPFSTP LHLPHPHSVI KTVPFTARTG KRTSRLLCEA 480
SLGEEMPL 488 
Gene Ontology
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR003104; Actin-bd_FH2/DRF_autoreg.
 IPR015425; FH2_actin-bd. 
Pfam
 PF02181; FH2 
SMART
 SM00498; FH2 
PROSITE
 PS51444; FH2 
PRINTS