CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027720
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GH10480p 
Protein Synonyms/Alias
 SkpA associated protein, isoform C; SkpA associated protein, isoform D 
Gene Name
 skap 
Gene Synonyms/Alias
 CG11963; Dmel_CG11963 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
74EANDIATKLKTDNLVacetylation[1]
272DNAEFRQKELFALRDacetylation[1]
348EAVKAAFKIITSDPKacetylation[1]
421LARDDLDKAADLAVHacetylation[1]
440VKLAREMKMDVNFEIacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 503 AA 
Protein Sequence
MASFLARTGG PLIETVRPAA IKKILGLAPI AVQQLRNLNV QEHVSYSLLN EAKIPTPRFA 60
VAKNGKEAND IATKLKTDNL VLKAQVLAGG RGKGTFKNGL KGGVRVVYDP QTAEELSSKM 120
IDQLLVTKQT GAAGRICKKV MVAERKFPRR EFYFAVMMER AFNGPVLIAS KEGGVDIEEV 180
AASSPDAILY EPIDIGTGLT SEQAEKIVKK VGLGGDGEDT HVQMLLNLYD LFVKKDALLV 240
EINPYAEDAM SGCFFALDAK LRFDDNAEFR QKELFALRDW TQEDPKEVEA AKYNLNYIAL 300
DGTIGCMVNG AGLAMATMDI IKLYGGEPAN FLDVGGGATA EAVKAAFKII TSDPKVLCIL 360
VNIFGGIMRC DVIAEGIISA TKDLNLNMPV VVRLQGTKVK EARELIRTSG LKILARDDLD 420
KAADLAVHLA QIVKLAREMK MDVNFEIPDA QKGKGDCKKD QKQPDSKGGK KSEKKDDKKS 480
DCTKKEEKKK EEKKDICEKK GKK 503 
Gene Ontology
 GO:0005813; C:centrosome; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0010824; P:regulation of centrosome duplication; IMP:FlyBase. 
Interpro
 IPR011761; ATP-grasp.
 IPR013650; ATP-grasp_succ-CoA_synth-type.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR005811; CoA_ligase.
 IPR017866; Succ-CoA_synthase_bsu_CS.
 IPR005809; Succ_CoA_synthase_bsu.
 IPR016102; Succinyl-CoA_synth-like. 
Pfam
 PF08442; ATP-grasp_2
 PF00549; Ligase_CoA 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS01217; SUCCINYL_COA_LIG_3 
PRINTS