CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041839
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Histone demethylase UTY 
Protein Synonyms/Alias
 Ubiquitously transcribed tetratricopeptide repeat 
Gene Name
 Uty 
Gene Synonyms/Alias
 mCG_121149 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
390SALTSRIKFLQAQLCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1212 AA 
Protein Sequence
MKSYGLSLTT AALGNEEKKM AAEKARGEGE EGSFSLTVEE KKALCGLDSS FFGFLTRCKD 60
GAKMKTLLNK AIHFYESLIV KAEGKVESDF FCQLGHFNLL LEDYSKALSS YQRYYSLQTD 120
YWKNAAFLYG LGLVYFYYNA FQWAIRAFQE VLYVDPNFCR AKEIHLRLGF MFKMNTDYES 180
SLKHFQLALI DCNVCTLSSV EIQFHIAHLY ETQRKYHSAK AAYEQLLQIE SLPSQVKATV 240
LQQLGWMHHN MDLIGDNTTK ERYAIQYLQK SLEEDPNSGQ SWYFLGRCYS CIGKVQDAFV 300
SYRQSIDKSE ASADTWCSIG VLYQQQNQPM DALQAYICAV QLDHGHAAAW MDLGILYESC 360
NQPQDAIKCY LNAARSKSCN NTSALTSRIK FLQAQLCNLP QSSLQNKTKL LPSIEEAWSL 420
PIPAELTSRQ GAMNTAQQSV SDTWNSVQTA SHHSVQQKVY TQCFTAQKLQ SFGKDQQPPF 480
QTGSTRYLQA ASTNDQNQNG NHTLPQNSKG DAQNHFLRIP TSEEQKIINF TKESKDSRSK 540
SLTSKTSRKD RDTSNICVNA KKHSNHIYQI SSVPISSLNN KESVSPDLII VDNPQLSVLV 600
GETIDNVDHD IGTCDKVNNV HLAIHKKPDN LSASSPSSAI STETLSLKLT EQTHIVTSFI 660
SPHSGLHTIN GEGHENLESS ASVNVGLRPR SQIIPSMSVS IYSSSTEVLK ACRSLGKNGL 720
SNGHILLDIC PPPRPPTSPY PPLPKEKLNP PTPSIYLENK RDAFFPPLHQ FCINPKNPVT 780
VIRGLAGALK LDLGLFSTKT LVEANNEHIV EVRTQLLQPA DENWDPSGTK KIWRYENKSS 840
HTTIAKYAQY QACSFQESLR EENERRTQVK DYSDNESTCS DNSGRRQKAP FKTIKCGINI 900
DLSDNKKWKL QLHELTKLPA FVRVVSAGNL LSHVGYTILG MNSVQLCMKV PGSRIPGHQE 960
NNNFCSVNIN IGPGDCEWFV VPEDYWGVLN DFCEKNNLNF LMSSWWPNLE DLYEANVPVY 1020
RFIQRPGDLV WINAGTVHWV QAIGWCNNIT WNVGPLTAFQ YKLAVERYEW NKLQSVKSVV 1080
PMVHLSWNMA RNIKVSDPKL FEMIKYCLLK ILKHCQTLRE ALVAAGKEVL WHGRINDEPA 1140
PYCSICEVEV FNLLFVTNES NSQKTYIVHC QNCARKTSGN LENFVVLEQY KMEDLIQVYD 1200
QFTLAPSLSS AS 1212 
Gene Ontology
 GO:0051864; F:histone demethylase activity (H3-K36 specific); IMP:MGI.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.
 GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:MGI.
 GO:0086003; P:cardiac muscle cell contraction; IMP:MGI.
 GO:0045184; P:establishment of protein localization; IDA:MGI.
 GO:0007507; P:heart development; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0031935; P:regulation of chromatin silencing; IMP:MGI. 
Interpro
 IPR003347; JmjC_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF02373; JmjC
 PF13181; TPR_8 
SMART
 SM00558; JmjC
 SM00028; TPR 
PROSITE
 PS51184; JMJC
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS