CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027141
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA0569 protein 
Protein Synonyms/Alias
  
Gene Name
 Zeb2 
Gene Synonyms/Alias
 mKIAA0569; Zfhx1b 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
676LSSVLSEKGLTSPINubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1248 AA 
Protein Sequence
DPLASATHQT IEPACCRSRA PSPCELPSDP LLSMKQPIMA DGPRCKRRKQ ANPRRKNVVN 60
YDNVVDAGSE TDEEDKLHIA EDDSLANPLD QDTSPASMPN HESSPHMSQG LLPREEEEEE 120
LRESVVEHSW HSGEILQASV AGPEEMKEDY DAMGPEATIQ TTINNGTVKN ANCTSDFEEY 180
FAKRKLEERD GHAVSIEEYL QRSDTAIIYP EAPEELSRLG TPEANGQEEN DLPPGTPDAF 240
AQLLTCPYCD RGYKRLTSLK EHIKYRHEKN EENFSCPLCS YTFAYRTQLE RHMVTHKPGT 300
DQHQMLTQGA GNRKFKCTEC GKAFKYKHHL KEHLRIHSGE KPYECPNCKK RFSHSGSYSS 360
HISSKKCIGL ISVNGRMRNN IKTGSSPNSV SSSPTNSAIT QLRNKLENGK PLSMSEQTGL 420
LKIKTEPLDF NDYKVLMATH GFSGSSPFMN GGLGATSPLG VHPSAQSPMQ HLGVGMEAPL 480
LGFPTMNSNL SEVQKVLQIV DNTVSRQKMD CKTEDISKLK GYHMKDPCSQ PEEQGVTSPN 540
IPPVGLPVVS HNGATKSIID YTLEKVNEAK ACLQSLTTDS RRQISNIKKE KLRTLIDLVT 600
DDKMIENHSI STPFSCQFCK ESFPGPIPLH QHERYLCKMN EEIKAVLQPH ENIVPNKAGV 660
FVDNKALLLS SVLSEKGLTS PINPYKDHMS VLKAYYAMNM EPNSDELLKI SIAVGLPQEF 720
VKEWFEQRKV YQYSNSRSPS LERTSKPLAP NSNPTTKDSL LPRSPVKPMD SITSPSIAEL 780
HNSVTSCDPP LRLTKSSHFT NIKAVDKLDH SRSNTPSPLN LSSTSSKNSH SSSYTPNSFS 840
SEELQAEPLD LSLPKQMREP KGIIATKNKT KATSINLDHN SVSSSSENSD EPLNLTFIKK 900
EFSNSNNLDN KSNNPVFGMN PFSAKPLYTP LPPQSAFPPA TFMPPVQTSI PGLRPYPGLD 960
QMSFLPHMAY TYPTGAATFA DMQQRRKYQR KQGFQGDLLD GAQDYMSGLD DMTDSDSCLS 1020
RKKIKKTESG MYACDLCDKT FQKSSSLLRH KYEHTGKRPH QCQICKKAFK HKHHLIEHSR 1080
LHSGEKPYQC DKCGKRFSHS GSYSQHMNHR YSYCKREAEE REAAEREARE KGHLEPTELL 1140
MNRAYLQSIT PQGYSDSEER ESMPRDGESE KEHEKEGEEG YGKLRRRDGD EEEEEEEEES 1200
ENKSMDTDPE TIRDEEETGD HSMDDSSEDG KMETKSDHEE DNMEDGME 1248 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0070412; F:R-SMAD binding; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0021846; P:cell proliferation in forebrain; IMP:MGI.
 GO:0021766; P:hippocampus development; IMP:MGI.
 GO:0001755; P:neural crest cell migration; IMP:MGI.
 GO:0001843; P:neural tube closure; IMP:MGI.
 GO:0043507; P:positive regulation of JUN kinase activity; IMP:MGI.
 GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:MGI.
 GO:0001756; P:somitogenesis; IMP:MGI. 
Interpro
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00389; HOX
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS