UniProt Accession

 WWM1_YEAST; P43582; D6VTM0 

Genbank Protein ID

 D50617; Z46255; BK006940 

Genbank Nucleotide ID

 BAA09228.1; CAA86342.1; DAA12430.1 

Protein Name

 WW domain-containing protein WWM1 

Protein Synonyms/Alias

 WW domain-containing protein interacting with metacaspase 

Gene Name

 WWM1 

Gene Synonyms/Alias

 YFL010C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
50	GTTWPRPKGPPPGVN	ubiquitination	[1, 2]
60	PPGVNNEKSSRQQAD	ubiquitination	[1, 2]
134	GTAPSTSKGSGHGGA	ubiquitination	[1]

Reference

 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Involved in apoptosis. May play a role in nuclear function controlling cellular proliferation coupled to mitochondrial biogenesis. Causes impaired growth when overexpressed. 

Sequence Annotation

 DOMAIN 9 43 WW.
 MOD_RES 75 75 Phosphoserine.
 MOD_RES 78 78 Phosphothreonine.  

Keyword

 Apoptosis; Complete proteome; Cytoplasm; Mitochondrion; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 211 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. 

Interpro

 IPR001202; WW_dom. 

Pfam

 PF00397; WW 

SMART

 SM00456; WW 

PROSITE

 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 

PRINTS