CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009153
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-rich repeat-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 Lrrc3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
70PADTVLLKLDANRISubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 DOMAIN 33 64 LRRNT.
 REPEAT 65 86 LRR 1.
 REPEAT 89 110 LRR 2.
 REPEAT 114 135 LRR 3.
 DOMAIN 145 198 LRRCT.  
Keyword
 Complete proteome; Leucine-rich repeat; Membrane; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 257 AA 
Protein Sequence
MGPRGRQSPS ATLAPSQGSC FFILFCLRLG ASCPQACQCP DHAGAVAVHC SSRGLQEIPR 60
DIPADTVLLK LDANRISRVP NGAFQHLPQL RELDLSHNAI EAIGPAAFSG LAGGLRLLDL 120
SHNRIRRIPK DALGKLSAKI RLSHNPLHCE CALQEALWEL KLDPDSVDEI ACHTSAQEQF 180
VGKPLIQVLD SGASFCSTHR KTTDVAMLVT MFGWFTMVIA YVVYYVRHNQ EDARRHLEYL 240
KSLPSAPVSK EPLSPVP 257 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR000372; LRR-contain_N. 
Pfam
 PF00560; LRR_1
 PF01462; LRRNT 
SMART
 SM00369; LRR_TYP
 SM00013; LRRNT 
PROSITE
 PS51450; LRR 
PRINTS