CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038120
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Plectin 
Protein Synonyms/Alias
  
Gene Name
 Plec 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
287EVERDLDKADGMIRLacetylation[1]
303FNDVQTLKDGRHPQGacetylation[2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 499 AA 
Protein Sequence
MTAKEKLLLW SQRMVEGYQG LRCDNFTTSW RDGRLFNAII HRHKPMLIDM NKVYRQTNLE 60
NLDQAFSVAE RDLGVTRLLD PEDVDVPQPD EKSIITYVSS LYDAMPRVPG AQDGVRANEL 120
QLRWQEYREL VLLLLQWIRH HTAAFEERKF PSSFEEIEIL WCQFLKFKET ELPAKEADKN 180
RSKVIYQSLE GAVQAGQLKI PPGYHPLDVE KEWGKLHVAI LEREKQLRSE FERLECLQRI 240
VSKLQMEAGL CEEQLNQADA LLQSDIRLLA SGKVAQRAGE VERDLDKADG MIRLLFNDVQ 300
TLKDGRHPQG EQMYRRVYRL HERLVAIRTE YNLRLKAGVG APVTQVTLQS TQRRPELEDS 360
TLRYLQDLLA WVEENQRRID SAEWGVDLPS VEAQLGSHRG MHQSIEEFRA KIERARNDES 420
QLSPATRGAY RDCLGRLDLQ YAKLLNSSKA RLRSLESLHG FVAAATKELM WLNEKEEEEV 480
GFDWSDRNTN MAAKKESYS 499 
Gene Ontology
 GO:0043292; C:contractile fiber; IDA:MGI.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0030056; C:hemidesmosome; IEA:Compara.
 GO:0045111; C:intermediate filament cytoskeleton; IEA:Compara.
 GO:0042383; C:sarcolemma; IEA:Compara.
 GO:0031581; P:hemidesmosome assembly; IEA:Compara. 
Interpro
 IPR001715; CH-domain.
 IPR018159; Spectrin/alpha-actinin. 
Pfam
 PF00307; CH 
SMART
 SM00033; CH
 SM00150; SPEC 
PROSITE
 PS50021; CH 
PRINTS