| Tag | Content |
|---|
| CPLM ID | CPLM-011881 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable phospholipid-transporting ATPase DNF3 |
Protein Synonyms/Alias | |
Gene Name | DNF3 |
Gene Synonyms/Alias | YMR162C; YM8520.11C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 857 | DRELAAKKMADICTS | ubiquitination | [1] | | 1208 | CRASPSQKALMVSNI | ubiquitination | [1] | | 1538 | RQGWTWDKDPSTFTR | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of phospholipids (Potential). |
Sequence Annotation | ACT_SITE 566 566 4-aspartylphosphate intermediate
MOD_RES 627 627 Phosphoserine. |
Keyword | ATP-binding; Complete proteome; Hydrolase; Magnesium; Membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1656 AA |
Protein Sequence | MGIADGQRRR SSSLRTQMFN KHLYDKYRGR TDDEIELEDI NESKTFSGSD NNDKDDRDET 60
SGNYAAEEDY EMEEYGSPDV SYSIITKILD TILDRRRTFH SKDGRHIPII LDHNAIEYKQ 120
AATKRDGHLI DERFNKPYCD NRITSSRYTF YSFLPRQLYA QFSKLANTYF FIVAVLQMIP 180
GWSTTGTYTT IIPLCVFMGI SMTREAWDDF RRHRLDKEEN NKPVGVLVKD GNNDAQEVYT 240
LPSSVVSSTA YLTKSAAAEN NPPLNDDRNS SQGHFLDTHF NNFELLKNKY NVHIHQKKWE 300
KLRVGDFVLL TQDDWVPADL LLLTCDGENS ECFVETMALD GETNLKSKQP HPELNKLTKA 360
ASGLANINAQ VTVEDPNIDL YNFEGNLELK NHRNDTIMKY PLGPDNVIYR GSILRNTQNV 420
VGMVIFSGEE TKIRMNALKN PRTKAPKLQR KINMIIVFMV FVVATISLFS YLGHVLHKKK 480
YIDQNKAWYL FQADAGVAPT IMSFIIMYNT VIPLSLYVTM EIIKVVQSKM MEWDIDMYHA 540
ETNTPCESRT ATILEELGQV SYIFSDKTGT LTDNKMIFRK FSLCGSSWLH NVDLGNSEDN 600
FEDNRDNTNS LRLPPKAHNG SSIDVVSIGD QNVLDRLGFS DAPIEKGHRP SLDNFPKSRN 660
SIEYKGNSSA IYTGRPSMRS LFGKDNSHLS KQASVISPSE TFSENIKSSF DLIQFIQRYP 720
TALFSQKAKF FFLSLALCHS CLPKKTHNES IGEDSIEYQS SSPDELALVT AARDLGYIVL 780
NRNAQILTIK TFPDGFDGEA KLENYEILNY IDFNSQRKRM SVLVRMPNQP NQVLLICKGA 840
DNVIMERLHD RELAAKKMAD ICTSTKERKD AEAELVLQQR KSLERMVDEE AMARTSLRNS 900
LSSVPRASLS LQAVRKSLSM KNSRTRDPEK QIDSIDQFLE TVKKSDQEIG SVVNKSRKSL 960
HKQQIEKYGP RISIDGTHFP NNNVPIDTRK EGLQHDYDTE ILEHIGSDEL ILNEEYVIER 1020
TLQAIDEFST EGLRTLVYAY KWIDIGQYEN WNKRYHQAKT SLTDRKIKVD EAGAEIEDGL 1080
NLLGVTAIED KLQDGVSEAI EKIRRAGIKM WMLTGDKRET AINIGYSCML IKDYSTVVIL 1140
TTTDENIISK MNAVSQEVDS GNIAHCVVVI DGATMAMFEG NPTYMSVFVE LCTKTDSVIC 1200
CRASPSQKAL MVSNIRNTDP NLVTLAIGDG ANDIAMIQSA DIGVGIAGKE GLQASRVSDY 1260
SIGQFRFLLK LLFVHGRYNY IRTSKFMLCT FYKEITFYFT QLIYQRYTMF SGSSLYEPWS 1320
LSMFNTLFTS LPVLCIGMFE KDLKPMTLLT VPELYSYGRL SQGFNWLIFM EWVILATTNS 1380
LIITFLNVVM WGMSSLSDNT MYPLGLINFT AIVALINVKS QFVEMHNRNW LAFTSVVLSC 1440
GGWLVWCCAL PILNNTDQIY DVAYGFYNHF GKDITFWCTS LVLALLPITL DIVYKTFKVM 1500
IWPSDSDIFA ELEQKSDIRK KLELGAYSEM RQGWTWDKDP STFTRYTDKV LSRPRTNSRA 1560
SAKTHNSSIY SMSNGNVDHS SKKNFFGNSS KKSSERYEVL PSGKLIKRPS LKTQSSKDSI 1620
GGNITTKLTK KLKLPSRNVE DEDVNQIIQA RLKDLE 1656 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0030140; C:trans-Golgi network transport vesicle; IDA:SGD. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro. GO:0000287; F:magnesium ion binding; IEA:InterPro. GO:0004012; F:phospholipid-translocating ATPase activity; IMP:SGD. GO:0006886; P:intracellular protein transport; IGI:SGD. GO:0045332; P:phospholipid translocation; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |