CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032115
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sec1 family domain-containing protein 1 
Protein Synonyms/Alias
 cDNA FLJ57213, highly similar to Sec1 family domain-containing protein 1 
Gene Name
 SCFD1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
67ISAISRSKLEDIANAubiquitination[1, 2, 3]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 583 AA 
Protein Sequence
MCLILKTAQE NQYGRLLHSD RDPIPDVPAV YFVMPTEENI DRMCQDLRNQ LYESYYLNFI 60
SAISRSKLED IANAALAASA VTQVAKVFDQ YLNFITLEDD MFVLCNQNKE LVSYRAINRP 120
DITDTEMETV MDTIVDSLFC FFVTLGAVPI IRCSRGTAAE MVAVKLDKKL RENLRDARNS 180
LFTGDTLGAG QFSFQRPLLV LVDRNIDLAT PLHHTWTYQA LVHDVLDFHL NRVNLEESSG 240
VENSPAGARP KRKNKKSYDL TPVDKFWQKH KGSPFPEVAE SVQQELESYR AQEDEVKRLK 300
SIMGLEGEDE GAISMLSDNT AKLTSAVSSL PELLEKKRLI DLHTNVATAV LEHIKARKLD 360
VYFEYEEKIM SKTTLDKSLL DIISDPDAGT PEDKMRLFLI YYISTQQAPS EADLEQYKKA 420
LTDAGCNLNP LQYIKQWKAF TKMASAPASY GSTTTKPMGL LSRVMNTGSQ FVMEGVKNLV 480
LKQQNLPVTR ILDNLMEMKS NPETDDYRYF DPKMLRGNDS SVPRNKNPFQ EAIVFVVGGG 540
NYIEYQNLVD YIKGKQGKHI LYGCSELFNA TQFIKQLSQL GQK 583 
Gene Ontology
 GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro. 
Interpro
 IPR027482; Sec-1-like_dom2.
 IPR001619; Sec1-like. 
Pfam
 PF00995; Sec1 
SMART
  
PROSITE
  
PRINTS