CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022222
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Double zinc ribbon and ankyrin repeat-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 DZANK1 
Gene Synonyms/Alias
 C20orf12; C20orf84 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
448PSGKLLAKKEQELASubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 REPEAT 605 636 ANK 1.
 REPEAT 640 669 ANK 2.
 ZN_FING 211 270 DZANK-type 1.
 ZN_FING 339 387 DZANK-type 2.
 MOD_RES 182 182 Phosphoserine.  
Keyword
 Alternative splicing; ANK repeat; Complete proteome; Metal-binding; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 752 AA 
Protein Sequence
MTAGSVCVPQ IIPLRVPQPG KANHEIDNNT LLEMKSDTPD VNIYYTLDGS KPEFLKRIGY 60
GENNTFKYIK PITLPDGKIQ VKAIAVSKDC RQSGIVTKVF HVDYEPPNIV SPEDNVENVL 120
KDSSRQEFKN GFVGSKLKKK YKNSENQRSW NVNLRKFPES PLEIPAYGGG SGSRPPTRQS 180
QSPGFAHVSG QKCLTSTEIM RIQRETDFLK CAHCLAPRPS DPFARFCQEC GSPVPPIFGC 240
RLPPPEGAQM GLCAECRSLV PMNTPICVVC EAPLALQLQP QASLHLKEKV ICRACGTGNP 300
AHLRYCVTCE GALPSSQESM CSGDKAPPPP TQKGGTISCY RCGRWNLWEA SFCGWCGAML 360
GIPAGCSVCP KCGASNHLSA RFCGSCGICV KSLVKLSLDR SLALAAEEPR PFSESLNIPL 420
PRSDVGTKRD IGTQTVGLFY PSGKLLAKKE QELASQKQRQ EKMSDHKPLL TAISPGRGYW 480
RRQLDHISAH LRCYAQNNPE FRALIAEPRM GKLISATVHE DGCEVSIRLN YSQVSNKNLY 540
LNKAVNFSDH LLSSAAEGDG GLCGSRSSWV SDYSQSTSDT IEKIKRIKNF KTKTFQEKKE 600
QLIPENRLLL KEVGPTGEGR VSVIEQLLDE GADPNCCDED NRPVITVAVM NKHHEAIPVL 660
VQRGADIDQQ WGPLRNTALH EATLLGLAGR ESTATLLGCN ASIQKKNAGG QTAYDLALNT 720
GDDLVTSLFA AKFGQGLEDQ LAQTRSLSLD DC 752 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR025874; DZR.
 IPR001876; Znf_RanBP2. 
Pfam
 PF12796; Ank_2
 PF12773; DZR 
SMART
 SM00248; ANK
 SM00547; ZnF_RBZ 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS