| Tag | Content |
|---|
| CPLM ID | CPLM-008771 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein SQS1 |
Protein Synonyms/Alias | Squelch of splicing suppression protein 1 |
Gene Name | SQS1 |
Gene Synonyms/Alias | YNL224C; N1269 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 76 | GRAFISPKTIEDYYF | ubiquitination | [1] | | 353 | PQLTEDIKCLSINGT | ubiquitination | [1] | | 521 | KHDTERFKTFETKSL | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | May be involved in splicing since overexpression antagonizes the suppression of splicing defects by SPP382 mutants. |
Sequence Annotation | DOMAIN 594 656 R3H.
DOMAIN 720 767 G-patch.
MOD_RES 105 105 Phosphoserine.
MOD_RES 217 217 Phosphoserine.
MOD_RES 255 255 Phosphoserine.
MOD_RES 334 334 Phosphoserine.
MOD_RES 343 343 Phosphoserine.
MOD_RES 345 345 Phosphoserine. |
Keyword | Complete proteome; Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 767 AA |
Protein Sequence | MAKRHSHYQG SRRRHARGSN SKKAGRGNAK GIQGRKIKKK PTPTNSWHNS SIPLGEGDLD 60
DVGADFNPGR AFISPKTIED YYFGRDAKSR SMKMGGLRPG NRYDSSTDLQ AGRAAFRKRP 120
MQFVKAKEVY DPSHNMIQKL RAKNETKNSE EIVEREADVF EEPGKMTSDV EYINNEDSEN 180
EDDDSQNSPS TDHSLSSNES KVEDGDLFFV DEEAQQSPDL TKIKRVCIEE IARPREVAIE 240
FDPILTIGKV ELSVSEGNES KEISVDVPNK GNKTYHPFAG YISNVLHGMH TSDSDNDELD 300
YEIETENNSE PLYESSASSE VDQGFNYVGQ RHNSRADNNL LPSPSPQLTE DIKCLSINGT 360
KTFEGNNDNL PSPASEELEF GFKEEDFVIN TNDIVVSNIR MGGVDNSYYL RCYRLLGDYD 420
FHWIDQDLLT DFVVDELGLP EDRLPAYLNF IKNSLIPKIE PAEPTYSDIP ISDSSDEGDS 480
YEGDSYEDDE DMASSVVHSD IEEGLDDLIA YTLKHDTERF KTFETKSLET KGKGKKKKLL 540
IDDALALDTE TLETLQSKFS KRIETKAKKR KAKEDFIDQE NRNSNDMLKK YPYGLHIQNI 600
KDEFESFLSR NNDRLTFPPL DPHGNKTVMK IAKHYNMKSS KIGKANHTSV VVEKIKKTKW 660
SSPNYSLIDQ LMRQRPVFMR IDIRRPREEQ AAFERTKTIR GKFHVKEGEI VGQNAPEIGN 720
ENIGRRMLEK LGWKSGEGLG IQGNKGISEP IFAKIKKNRS GLRHSES 767 |
Gene Ontology | GO:0030686; C:90S preribosome; IDA:SGD. GO:0005737; C:cytoplasm; IDA:SGD. GO:0005730; C:nucleolus; IDA:SGD. GO:0030687; C:preribosome, large subunit precursor; IDA:SGD. GO:0030688; C:preribosome, small subunit precursor; IDA:SGD. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0030490; P:maturation of SSU-rRNA; IGI:SGD. GO:0000398; P:mRNA splicing, via spliceosome; IGI:SGD. GO:0032781; P:positive regulation of ATPase activity; IMP:SGD. GO:0051096; P:positive regulation of helicase activity; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |