| Tag | Content |
|---|
| CPLM ID | CPLM-001763 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytochrome c peroxidase, mitochondrial |
Protein Synonyms/Alias | CCP |
Gene Name | CCP1 |
Gene Synonyms/Alias | CCP; CPO; YKR066C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 157 | AGLQNGFKFLEPIHK | acetylation | [1] | | 216 | GRLPDADKDADYVRT | acetylation | [1] | | 316 | PKYLSIVKEYANDQD | acetylation | [1] | | 345 | ENGITFPKDAPSPFI | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Destroys radicals which are normally produced within the cells and which are toxic to biological systems. |
Sequence Annotation | ACT_SITE 119 119 Proton acceptor.
ACT_SITE 258 258 Tryptophan radical intermediate.
METAL 242 242 Iron (heme axial ligand).
MOD_RES 220 220 Phosphotyrosine. |
Keyword | 3D-structure; Complete proteome; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Mitochondrion; Organic radical; Oxidoreductase; Peroxidase; Phosphoprotein; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 361 AA |
Protein Sequence | MTTAVRLLPS LGRTAHKRSL YLFSAAAAAA AAATFAYSQS QKRSSSSPGG GSNHGWNNWG 60
KAAALASTTP LVHVASVEKG RSYEDFQKVY NAIALKLRED DEYDNYIGYG PVLVRLAWHT 120
SGTWDKHDNT GGSYGGTYRF KKEFNDPSNA GLQNGFKFLE PIHKEFPWIS SGDLFSLGGV 180
TAVQEMQGPK IPWRCGRVDT PEDTTPDNGR LPDADKDADY VRTFFQRLNM NDREVVALMG 240
AHALGKTHLK NSGYEGPWGA ANNVFTNEFY LNLLNEDWKL EKNDANNEQW DSKSGYMMLP 300
TDYSLIQDPK YLSIVKEYAN DQDKFFKDFS KAFEKLLENG ITFPKDAPSP FIFKTLEEQG 360
L 361 |
Gene Ontology | GO:0005758; C:mitochondrial intermembrane space; IDA:SGD. GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0004130; F:cytochrome-c peroxidase activity; IDA:SGD. GO:0020037; F:heme binding; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0034599; P:cellular response to oxidative stress; IMP:SGD. GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |