| Tag | Content |
|---|
| CPLM ID | CPLM-021117 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable E3 ubiquitin-protein ligase makorin-2 |
Protein Synonyms/Alias | |
Gene Name | Mkrn2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 319 | NELIEAFKQGMGKKA | ubiquitination | [1] | | 328 | GMGKKACKYFEQGKG | ubiquitination | [1] | | 334 | CKYFEQGKGTCPFGS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). |
Sequence Annotation | ZN_FING 2 29 C3H1-type 1.
ZN_FING 31 58 C3H1-type 2.
ZN_FING 165 192 C3H1-type 3.
ZN_FING 238 292 RING-type.
ZN_FING 321 350 C3H1-type 4.
REGION 193 222 Makorin-type Cys-His. |
Keyword | Complete proteome; Ligase; Metal-binding; Reference proteome; Repeat; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 416 AA |
Protein Sequence | MSTKQVTCRY FMHGVCREGS QCLFSHDLAN SKPSTICKYY QKGYCAYGAR CRYDHTKPPA 60
AAGGAVGPAP NPSPSSGLHS PHPSPDIATS VMRTHSNEPG KREKKTLVLR DRNLTGLAED 120
KTPPSKVNNP GGCSDPQTSP EMKPHSYLDA IRTGLDDLEA SSSYSNEPQL CPYAAAGECR 180
FGDACVYLHG DMCEICRLQV LHPFDPEQRK AHEKMCMSTF EHEMEKAFAF QASQDKVCSI 240
CMEVILEKAS ASERRFGILS NCSHTYCLSC IRQWRCAKQF ENPIIKSCPE CRVISEFVIP 300
SVYWVEDQNK KNELIEAFKQ GMGKKACKYF EQGKGTCPFG SKCLYRHAYP DGRLAEPEKP 360
RKQLSSEGTV RFFNSVRLWD FIENRETRQV PSTDDVDVTE LGDLFMHLSG VESSEP 416 |
Gene Ontology | GO:0005622; C:intracellular; ISS:UniProtKB. GO:0016874; F:ligase activity; IEA:UniProtKB-KW. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |