| Tag | Content |
|---|
| CPLM ID | CPLM-024347 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tetratricopeptide repeat protein 30A2 |
Protein Synonyms/Alias | TPR repeat protein 30A2 |
Gene Name | Ttc30a2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 122 | LRLQAAIKYSEGDLP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Required for polyglutamylation of axonemal tubulin (By similarity). Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity). |
Sequence Annotation | REPEAT 11 44 TPR 1.
REPEAT 45 78 TPR 2.
REPEAT 153 186 TPR 3.
REPEAT 188 220 TPR 4.
REPEAT 395 423 TPR 5.
REPEAT 424 456 TPR 6.
REPEAT 458 491 TPR 7.
REPEAT 543 576 TPR 8. |
Keyword | Cell projection; Cilium; Cilium biogenesis/degradation; Coiled coil; Complete proteome; Reference proteome; Repeat; TPR repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 664 AA |
Protein Sequence | MAGLSNSQIP DGEFTAVVYR LIRDSRYSEA VQLLSAELQR SSRSRAGLSL LAYCYYRLQE 60
FELAAECYEQ LSQMHPELEQ YRLYQAQALY KACLYPEATR VAFLLDNPTF YSRVLRLQAA 120
IKYSEGDLPG ARSLVEQLLS GEAGEDSGGE NDPDGLVNMG CLLYKEGHYE AACSKFFAAL 180
QASGYQPDVS YNLALACYSN RHYAPALKHI ANIIERGIRQ HPELGVGMTT EGIDVRSVGN 240
TVVLHQTALV EAFNLKAAIE YQLRNYEAAQ EALTDMPPRA EEELDPVTLH NQALMNMDAK 300
PTEGFEKLQF LLQQNPFPPE TFGNLLLLYC KYEYFDLAAD VLAENAHLTY KFLTPYLYDF 360
LDAMITCQTA PEEAFIKLDG LAGMLTEQLR RLTKQVQEAR HNRDDEVVIK AVNEYDETLE 420
KYIPVLMAQA KIYWNLENYP MVEKIFRKSV EFCNDHDVWK LNVAHVLFMQ ENKYKEAIGF 480
YEPIVKKNYD NILSVSAIVL ANLCVSYIMT SQNEEAEELM RKIEKEEEQL SYGDPDKKIY 540
HLCIVNLVIG TLYCAKGNYD FGISRVIKSL EPYHKKLGTD TWYYAKRCFL SLLENMSKHT 600
IMLRDSVIQE CVQFLEHCEI FGRNIPAVIE QPLEEERMHI GKNTVTYESR QLKALIYEII 660
GWNM 664 |
Gene Ontology | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. GO:0030030; P:cell projection organization; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |