| Tag | Content |
|---|
| CPLM ID | CPLM-008022 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | COPII coat assembly protein SEC16 |
Protein Synonyms/Alias | Protein transport protein SEC16 |
Gene Name | SEC16 |
Gene Synonyms/Alias | YPL085W; LPF1W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 395 | GQNDFTGKNIENESQ | ubiquitination | [1] | | 502 | SMQTSTEKIAEQKFS | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy. |
Sequence Annotation | MOD_RES 28 28 Phosphoserine.
MOD_RES 73 73 Phosphoserine.
MOD_RES 144 144 Phosphoserine.
MOD_RES 313 313 Phosphoserine.
MOD_RES 472 472 Phosphoserine.
MOD_RES 483 483 Phosphoserine.
MOD_RES 595 595 Phosphothreonine.
MOD_RES 607 607 Phosphoserine.
MOD_RES 660 660 Phosphoserine.
MOD_RES 663 663 Phosphoserine.
MOD_RES 665 665 Phosphoserine.
MOD_RES 674 674 Phosphoserine.
MOD_RES 678 678 Phosphoserine.
MOD_RES 681 681 Phosphoserine.
MOD_RES 701 701 Phosphoserine.
MOD_RES 704 704 Phosphoserine.
MOD_RES 706 706 Phosphoserine.
MOD_RES 759 759 Phosphoserine.
MOD_RES 762 762 Phosphoserine.
MOD_RES 765 765 Phosphoserine.
MOD_RES 768 768 Phosphoserine.
MOD_RES 843 843 Phosphoserine.
MOD_RES 1511 1511 Phosphoserine.
MOD_RES 1515 1515 Phosphoserine.
MOD_RES 1602 1602 Phosphoserine.
MOD_RES 1603 1603 Phosphoserine.
MOD_RES 1611 1611 Phosphoserine.
MOD_RES 1617 1617 Phosphoserine.
MOD_RES 1778 1778 Phosphoserine.
MOD_RES 1875 1875 Phosphoserine.
MOD_RES 1973 1973 Phosphoserine.
MOD_RES 1986 1986 Phosphoserine.
MOD_RES 1992 1992 Phosphoserine.
MOD_RES 2049 2049 Phosphothreonine.
MOD_RES 2130 2130 Phosphoserine. |
Keyword | 3D-structure; Autophagy; Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 2195 AA |
Protein Sequence | MTPEAKKRKN QKKKLKQKQK KAAEKAASHS EEPLELPEST INSSFNDDSV NRTESDIASK 60
SDVPPVSSST NISPANETQL EIPDTQELHH KLLNDSDQHD ITADSNDLPD NSIVEHDSVI 120
TQTKPAMSQE YEETAAHLSS RNPSLDVVAG ELHNNNEHTQ KIAVSAVEED SFNEEEGENH 180
DSIIISSLND ATPSQYNHFL PSDGNLLSPE LSSGDTPTHN VPLGTKDNEI NDDEYCNDKE 240
ISLNANNVLP DELSKEEDER LKLETHVSTE EKKQDIADQE TAENLFTSST EPSENKIRNS 300
GDDTSMLFQD DESDQKVPWE EDVKKDFHNE NTNNTQESAP NTDDRDKGYE GNEALKKSES 360
CTAADERSYS EETSEDIFHG HDKQVVEGQN DFTGKNIENE SQKLMGEGNH KLPLSAEADI 420
IEPGKDIQDQ AEDLFTQSSG DLGEVLPWES TDKNADVTSK SQEKHEDLFA ASGNDEKLPW 480
EVSDGEVSSG KTENSMQTST EKIAEQKFSF LENDDDLLDD DDSFLASSEE EDTVPNTDNT 540
TNLTSKPVEE KKASRYKPII EEEAGMRQEQ VHFTNTTGIV TPQQFHGLTK TGLGTPNQQV 600
SVPNIVSPKP PVVKDNRSNF KINEEKKKSD AYDFPLEIIS ESSKKGHAKP VAVPTQRFGS 660
GNSFSSLDKP IPQSRKGSNN SNRPPVIPLG TQEPRSSRTN SAISQSPVNY AFPNPYKIQQ 720
LQQAPIQSGM PLPNTNIPPP ALKVETTVSA PPIRARGVSN ASVGSSASFG ARHATQYGLN 780
NGVPPVSPYG QATINLPTAN KYAPVSPTVQ QKQYPSVVQN LGASAVNTPN FVKTHRGHTS 840
SISSYTPNQN EHASRYAPNY QQSYQVPYTS QPVGPVAGNS SYQSQTRSSY AVPMMPQAQT 900
SASIQPHANI QPPTGILPLA PLRPLDPLQA ATNLQPRASN ITAANSLPLA NLPLAENILP 960
EIITHRATSS VAPPRQENNP IKIDNEALLR RQFPIFHWSA ANKVVYAVPP IPDQSQYMIS 1020
SSIVQEIKVT PIDQIIKPND MLKSFPGPLG SAKLKKKDLT KWMETTIKSI SENESSTDMT 1080
IWQLLEMKLN DKVNWKNISK LLYNSDELLM YLSQPFPNGD MIPNAYRLDI NCQMRVLAFL 1140
QTGNHDEALR LALSKRDYAI ALLVGSLMGK DRWSEVIQKY LYEGFTAGPN DQKELAHFLL 1200
LIFQVFVGNS KMAIKSFYTN NETSQWASEN WKSIVAAVLI NIPENNEDPL LIPPVVLEFL 1260
IEFGIFLTKK GLTAAASTLF IIGNVPLSNE PVMADSDVIF ESIGNMNTFE SILWDEIYEY 1320
IFSYDPKFKG FSSILPQKIY HASLLQEQGL NSLGTKYTDY LSSSVRKLPK KDILTINLTR 1380
ELSEVASRLS ESNTGWLAKP KLSSVWGQLD KSFNKYIGGD DIDALNKKND KKKVFDGFTP 1440
GSSANSSTVD LTQTFTPFQA QVTSQSYVDT TALLHNAHNV PSHSVLHSKP SNVSKGLVEA 1500
NLPYTHRIGD SLQGSPQRIH NTQFAAAEPQ MASLRRVRTD QHTNEKALKS QQILEKKSTA 1560
YTPQFGQNHS VPMEKSNSNV PSLFADFPAP PKLGTVPSNY VSSPDLVRRE SIISTGSEFL 1620
PPPKIGVPTK ANSSQGSLMY SPSVEALPID PVVPQVHETG YNDFGNKHSQ KSMPEDESHT 1680
SHDNSNADQN TLKDSADVTD ETMDIEGPGF NDVKNLLPME PNHQPTSTVN PIQTISDDIQ 1740
PILQTNVEVR GTDASKMENS LPSIENERSS EEQPENISKS ASSAYLPSTG GLSLENRPLT 1800
QDENSISETV QSTYLPAGSI SMEAKPISQV QDVPRNVNNK ASKLVEQHMA PPKPKSTDAT 1860
KMNYSPYVPQ STAASADGDE STILKTSPAI YARTHQAHAS NPSQYFPLVN QANETASFEL 1920
SESTSQAQSN GNVASENRFS PIKKAEVVEK DTFQPTIRKA STNQYRAFKP LESDADKYND 1980
VIEDESDDDN MSTDEAKNRK EEKKNVNMKK ETKPSNKDID DKSNGWFGWL KKDTGDKKVY 2040
KAKLGHKNTL YYDEKLKRWV NKDATEEEKQ KIIESSAPPP PPIVKRKDGG PKTKPRSGPI 2100
NNSLPPVHAT SVIPNNPITG EPLPIKTSPS PTGPNPNNSP SPSSPISRIS GVNLTSKKAN 2160
GLDDLLSLAG GPKPASTRRK KKTARGYVNV MDNIQ 2195 |
Gene Ontology | GO:0070971; C:endoplasmic reticulum exit site; IDA:SGD. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0012507; C:ER to Golgi transport vesicle membrane; IDA:SGD. GO:0043495; F:protein anchor; IDA:SGD. GO:0006914; P:autophagy; IEA:UniProtKB-KW. GO:0048208; P:COPII vesicle coating; IDA:SGD. GO:0070973; P:protein localization to endoplasmic reticulum exit site; IMP:SGD. GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
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SMART | |
PROSITE | |
PRINTS | |