CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033049
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mitogen-activated protein kinase kinase kinase MLT 
Protein Synonyms/Alias
  
Gene Name
 ZAK 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
52KKLLKIEKEAEILSVubiquitination[1]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 138 AA 
Protein Sequence
MSSLGASFVQ IKFDDLQFFE NCGGGSFGSV YRAKWISQDK EVAVKKLLKI EKEAEILSVL 60
SHRNIIQFYG VILEPPNYGI VTEYASLGSL YDYINSNRSE EMDMDHIMTW ATDVAKGMHY 120
LHMEAPVKVI HRDLKSRN 138 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0000287; F:magnesium ion binding; IEA:Compara.
 GO:0004709; F:MAP kinase kinase kinase activity; IEA:Compara.
 GO:0000186; P:activation of MAPKK activity; IEA:GOC.
 GO:0007010; P:cytoskeleton organization; IEA:Compara.
 GO:0000165; P:MAPK cascade; IEA:GOC. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom. 
Pfam
 PF07714; Pkinase_Tyr 
SMART
  
PROSITE
 PS50011; PROTEIN_KINASE_DOM 
PRINTS