CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039656
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidate phosphatase LPIN1 
Protein Synonyms/Alias
  
Gene Name
 LPIN1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
103PFHVRFGKMGVLRSRubiquitination[1]
939DHVFPLLKRSHSSDFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 975 AA 
Protein Sequence
MGEQDGIRSS SWETSQGKSS PDSAWSWIPI MRDPGWIRNV WSSNINVQTM NYVGQLAGQV 60
FVTVKELYKG LNPATLSGCI DIIVIRQPNG NLQCSPFHVR FGKMGVLRSR EKVVDIEING 120
ESVDLHMKLG DNGEAFFVQE TDNDQEVIPM HLATSPILSE GASRMECQLK RGSVDRMRGL 180
DPSTPAQVIA PSETPSSSSV VKKRRKRRRK SQLDSLKRDD NMNTSEDEDM FPIEMSSDEA 240
MELLESSRTL PNDIPPFQDD IPEENLSLAV IYPQSASYPN SDREWSPTPS SLVDCKRTAP 300
HLAVAAEGGL SSSCPPQSSL FHPSESPSGS RPSTPKSDSE LVSKSTERTG QKNPEMLWLW 360
GELPQAAKSS SPHKMKESSP LSSRKICDKS HFQAIHSESS DTFSDQSPTL VGGALLDQNK 420
PQTEMQFVNE EDLETLGAAA PLLPMIEELK PPSASVVQTA NKTDSPSRKR DKRSRHLGAD 480
GVYLDDLTDM DPEVAALYFP KNGDPSGLAK HASDNGARSA NQSPQSVGSS GVDSGVESTS 540
DGLRDLPSIA ISLCGGLSDH REITKDAFLE QAVSYQQFVD NPAIIDDPNL VVKIGSKYYN 600
WTTAAPLLLA MQAFQKPLPK ATVESIMRDK MPKKGGRWWF SWRGRNTTIK EESKPEQCLA 660
GKAHSTGEQP PQLSLATRVK HESSSSDEER AAAKPSNAGH LPLLPNVSYK KTLRLTSEQL 720
KSLKLKNGPN DVVFSVTTQY QGTCRCEGTI YLWNWDDKVI ISDIDGTITR SDTLGHILPT 780
LGKDWTHQGI AKLYHKVSQN GYKFLYCSAR AIGMADMTRG YLHWVNERGT VLPQGPLLLS 840
PSSLFSALHR EVIEKKPEKF KVQCLTDIKN LFFPNTEPFY AAFGNRPADV YSYKQVGVSL 900
NRIFTVNPKG ELVQEHAKTN ISSYVRLCEV VDHVFPLLKR SHSSDFPCSD TFSNFTFWRE 960
PLPPFENQDI HSASA 975 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0008195; F:phosphatidate phosphatase activity; IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0031532; P:actin cytoskeleton reorganization; IEA:Compara.
 GO:0032869; P:cellular response to insulin stimulus; IEA:Compara.
 GO:0009062; P:fatty acid catabolic process; IEA:Compara.
 GO:0000266; P:mitochondrial fission; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0031100; P:organ regeneration; IEA:Compara.
 GO:0031065; P:positive regulation of histone deacetylation; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0045598; P:regulation of fat cell differentiation; IEA:Compara.
 GO:0031529; P:ruffle organization; IEA:Compara.
 GO:0006642; P:triglyceride mobilization; IEA:Compara. 
Interpro
 IPR023214; HAD-like_dom.
 IPR026058; LIPIN.
 IPR007651; Lipin_N.
 IPR013209; LNS2. 
Pfam
 PF04571; Lipin_N
 PF08235; LNS2 
SMART
 SM00775; LNS2 
PROSITE
  
PRINTS