CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028351
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Structural maintenance of chromosomes protein 
Protein Synonyms/Alias
  
Gene Name
 Smc1b 
Gene Synonyms/Alias
 mCG_117302 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
812QKRLEFEKQKTRLNIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Nucleus. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1248 AA 
Protein Sequence
MGHLELLLVE NFKSWRGRQV IGPFKRFTCI IGPNGSGKSN VMDALSFVMG EKTTNLRVKN 60
IQELIHGAHT GKPVSSSASV TIIYIEDSGE EKTFTRIIRG GCSEYHFGDK PVSRSVYVAQ 120
LENIGIIVKA QNCLVFQGTV ESISMKKPKE RTQFFEEIST SGEFIGEYEA KKKKLQKAEE 180
DAQFHFNVKK NVAAERKHAK IEKEEAEHYQ NLLEELKINK IQLMLFQLYY NEEKINVLNT 240
ELEQMDGNLS VVKDTLSHHE NIFKAKKKDY GMLTRQLQQT AKELKSVEAI LNQKRPQYIK 300
AKENTSHHLK KLDLSKKLIT DNEKQCSKQE DGIRALVAEL ADLDRAWKSF EKQMEEKILQ 360
KGRDIELENS QLDRYKLLKE QVRRKVGIMT QQLEKLQWEQ KAEKERLAFE KRRHGDTQGN 420
LKQIKEQIEE HKKRIEKLEE YTKTCMDCLE DKKQQEEALK KEIENTKSRM SEVNEELSLI 480
RNELQNAGID NHEGKRQQKR AEVLEHLKRL YPDSVFGRLL DLCHPIHKKY QLAVTKLFGR 540
YMVAIVVASE KIAKDCIRFL KAERAEPETF LALDYLDIKP INERLREIKG CKMMIDVIKT 600
QFPQLKKVIQ FVCGNGLVCE TVEEARHIAF GGPERRKAVA LDGTLFLKSG VISGGSSDLK 660
HKALCWDEKE LHNLRDKRSQ LVQELKELMK TLRKETDLKQ IQTLVQGTNT RLKYSQNELE 720
MIKKKHLATF YREQSQLQSE LLNIDSQCTM LSEGINKQQQ KIEEFQDKID EVEDDIFQDF 780
CEEIGVENIR EFENKHVKQQ QENDQKRLEF EKQKTRLNIQ LEYSRNQLKK KLNNIDTLKT 840
TIQKGKEDID NLKKTEEECL KIVEELMVKQ EQIKEVLATQ SSNIEKIHIQ IEEERKKVLA 900
VDREVGKLQK EVVIIQGSLE QKLLEKHNLL LDCKVQDIDI SLVLGSLEDI IEMELTETES 960
TQATADIYEK EASIQIDYSP LREDLKALQS DKEVEAHLTL LLQQVASQEN TLLKTTAPNL 1020
RAQENLKTVR DKFQESADVF EASRKEARIC RQEFEQVKRR RYDAFSQCFE HISVSIDQIY 1080
KKLCRNNSAQ AFLSPENPEE PYLDGISYNC VAPGKRFMPM DNLSGGEKCV AALALLFAVH 1140
SFRPAPFFVL DEVDAALDNT NIGKVSSYIK EQSQEQFQMI IISLKEEFYS KADALIGVYP 1200
EHNECMFSHV LTLDLSKYPD TEDQEGSRSH RKPRVPRVSM SPKSPQSR 1248 
Gene Ontology
 GO:0000775; C:chromosome, centromeric region; IDA:MGI.
 GO:0000800; C:lateral element; IDA:MGI.
 GO:0034991; C:nuclear meiotic cohesin complex; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0030261; P:chromosome condensation; IEA:InterPro.
 GO:0006310; P:DNA recombination; IEA:InterPro.
 GO:0006281; P:DNA repair; IEA:InterPro.
 GO:0007126; P:meiosis; IPI:MGI.
 GO:0007062; P:sister chromatid cohesion; IDA:MGI. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR003395; RecF/RecN/SMC.
 IPR024704; SMC.
 IPR010935; SMC_hinge. 
Pfam
 PF06470; SMC_hinge
 PF02463; SMC_N 
SMART
 SM00968; SMC_hinge 
PROSITE
  
PRINTS