UniProt Accession

 PTSN_ECOLI; P69829; P31222; Q2M908 

Genbank Protein ID

 U12684; D12938; Z27094; U18997; U00096; AP009048 

Genbank Nucleotide ID

 AAB60165.1; BAA02317.1; CAA81619.1; AAA58006.1; AAC76236.1; BAE77248.1 

Protein Name

 Nitrogen regulatory protein 

Protein Synonyms/Alias

 Enzyme IIA-NTR; PTS system EIIA component; Phosphotransferase enzyme IIA component 

Gene Name

 ptsN 

Gene Synonyms/Alias

 rpoP; yhbI; b3204; JW3171 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
59	EAILTREKMGSTGIG	acetylation	[1]
75	GIAIPHGKLEEDTLR	acetylation	[1]
129	HTLSLVAKRLADKTI	acetylation	[1]
134	VAKRLADKTICRRLR	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Seems to have a role in regulating nitrogen assimilation (By similarity). 

Sequence Annotation

 DOMAIN 12 156 PTS EIIA type-2.
 ACT_SITE 73 73 Tele-phosphohistidine intermediate (By  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Kinase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 163 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004857; F:enzyme inhibitor activity; IMP:EcoCyc.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0030295; F:protein kinase activator activity; IDA:EcoCyc.
 GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
 GO:0005351; F:sugar:hydrogen symporter activity; IEA:InterPro.
 GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
 GO:0032412; P:regulation of ion transmembrane transporter activity; IMP:EcoCyc. 

Interpro

 IPR016152; PTrfase/Anion_transptr.
 IPR002178; PTS_EIIA_2.
 IPR006320; PTS_Nitro_regul. 

Pfam

 PF00359; PTS_EIIA_2 

SMART

  

PROSITE

 PS51094; PTS_EIIA_TYPE_2
 PS00372; PTS_EIIA_TYPE_2_HIS 

PRINTS