CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020687
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Secernin-1 
Protein Synonyms/Alias
  
Gene Name
 Scrn1 
Gene Synonyms/Alias
 Kiaa0193 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
319DDVKLVPKAQSPCFGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Exocytosis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 414 AA 
Protein Sequence
MSGAPPSYSF VALPPRAKDG LVVFGKNSAR PRDEVQEVVY FPAVDHDAES KVECTYISID 60
QVPRTHAIVI SRPAWLWGAE MGANEHGVCI ANEAINAREP AAETEALLGM DLVRLGLERG 120
TTAKEALDII VSLLDEHGQG GNYYEDAHSC HSFQSAYLLV DRDEAWVLET VGKYWAAERI 180
TEGVRCICNH LSLATKLDEE HPELRTYAQS QGWWTGDDEF NFAQVFSPAD DRLDCCAGQD 240
SLEKQEESIT VQTMINILRD KASGVCIDSE SFLTTASIVS VLPQNRSSPC IHYFTGTPDP 300
SRSIFKPFIF VDDVKLVPKA QSPCFGDDDP AKKEPRFQEK PDRRHELYKA HEWARAVIES 360
DEEQGRTLRK TMLELEKQGL EAMDEILSSP EPPDPAEVGD LFYDCVDTEM KFFK 414 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0031965; C:nuclear membrane; IEA:Compara.
 GO:0016805; F:dipeptidase activity; IEA:InterPro.
 GO:0006887; P:exocytosis; ISS:UniProtKB.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR005322; Peptidase_C69. 
Pfam
 PF03577; Peptidase_C69 
SMART
  
PROSITE
  
PRINTS