CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027517
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein tyrosine phosphatase 61F, isoform D 
Protein Synonyms/Alias
 Protein tyrosine phosphatase 61F, isoform E 
Gene Name
 Ptp61F 
Gene Synonyms/Alias
 CG9181; Dmel_CG9181 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
248NGAESIGKELSKDALacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 431 AA 
Protein Sequence
MVWEQKSRAV LMLNKLMEKK QIKCHLYWPN EMGADKALKL PHVKLTVELV RLETYQNFVR 60
RWFKLTDLET QQSREVMQFH YTTWPDFGIP SSPNAFLKFL QQVRDSGCLS RDVGPAVVHC 120
SAGIGRSGTF CLVDCCLVLI DKYGECNVSK VLCELRSYRM GLIQTADQLD FSYQAIIEGI 180
KKLHDPTFLD AEEPLISNDT ETHTLDELPP PLPPRVQSLN LPLAPNSGGI LSLNMRAAQA 240
NGAESIGKEL SKDALNNFIN QHDMIHDAEV ADSRPLPPLP VRAFNDSDSD EDYLLDDDDE 300
DDTDEDEEYE TINEHDADPV NGHVPATTQP HADDVNANNE KPAVPVDEQH KANGIDPIPG 360
QLPASPENEL KRRKRNEYQA SLEQKVNDMK RKQRENEDKQ LAAKKRRSLL TYIAAGVVVG 420
VICAYAYTKL G 431 
Gene Ontology
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF00102; Y_phosphatase 
SMART
 SM00194; PTPc 
PROSITE
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00700; PRTYPHPHTASE.