UniProt Accession

 H0Y9K2_HUMAN; H0Y9K2 

Genbank Protein ID

 AC109992; AC134509 

Genbank Nucleotide ID

  

Protein Name

 Anthrax toxin receptor 1 

Protein Synonyms/Alias

  

Gene Name

 ATR 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
57	HMKKSLEKFVGDATR	ubiquitination	[1]
68	DATRLTDKLLELCNK	ubiquitination	[1]
75	KLLELCNKPVDGSSS	ubiquitination	[1]
194	EFNSLINKCLRKDAE	ubiquitination	[1]
244	LTKLYKEKGVYMTGK	ubiquitination	[1]
251	KGVYMTGKELRQCML	ubiquitination	[1, 2]
267	KSAALSEKLKVFREF	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 457 AA 

Protein Sequence

Gene Ontology

 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. 

Interpro

 IPR011009; Kinase-like_dom.
 IPR000403; PI3/4_kinase_cat_dom.
 IPR018936; PI3/4_kinase_CS. 

Pfam

 PF00454; PI3_PI4_kinase 

SMART

 SM00146; PI3Kc 

PROSITE

 PS00916; PI3_4_KINASE_2
 PS50290; PI3_4_KINASE_3 

PRINTS