CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041979
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Calcineurin binding protein 1, isoform CRA_b 
Protein Synonyms/Alias
 Calcineurin-binding protein cabin-1 
Gene Name
 CABIN1 
Gene Synonyms/Alias
 hCG_41092 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
78AVSSGDEKEGLKHPGubiquitination[1]
82GDEKEGLKHPGLILKubiquitination[1]
374FLPSRLRKLDPEEEDubiquitination[1]
394YEVQSEAKLESFPSIubiquitination[1]
635EEIDKNLKSLERCQSubiquitination[1]
656LYEAGDYKAVVHLLRubiquitination[1]
947LPEFDSYKTSTVSADubiquitination[1]
1112SFASRQLKQWRGELPubiquitination[1]
1138DSMLETAKHCFTSAAubiquitination[1]
1227SILKLLGKPDSGVGAubiquitination[1]
1345SQAGATGKDLQGATEacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2141 AA 
Protein Sequence
MIRIAALNAS STIEDDHEGS FKSHKTQTKE AQEAEAFALY HKALDLQKHD RFEESAKAYH 60
ELLEASLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA AQREDLETAM EFYLEAVMLD 120
STDVNLWYKI GHVALRLIRI PLARHAFEEG LRCNPDHWPC LDNLITVLYT LSDYTTCLYF 180
ICKALEKDCR YSKGLVLKEK IFEEQPCLRK DSLRMFLKCW KCLGESLLAM YNHLTTCEPP 240
RPSLGKRIDL SDYQDPSQPL ESSMVVTPVN VIQPSTVSTN PAVAVAEPVV SYTSVATTSF 300
PLHSPGLLET GAPVGDISGG DKSKKGVKRK KISEESGETA KRRSARVRNT KCKKEEKVDF 360
QELLMKFLPS RLRKLDPEEE DDSFNNYEVQ SEAKLESFPS IGPQRLSFDS ATFMESEKQD 420
VHEFLLENLT NGGILELMMR YLKAMGHKFL VRWPPGLAEV VLSVYHSWRR HSTSLPNPLL 480
RDCSNKHIKD MMLMSLSCME LQLDQWLLTK GRSSAVSPRN CPAGMVNGRF GPDFPGTHCL 540
GDLLQLSFAS SQRDLFEDGW LEFVVRVYWL KARFLALQGD MEQALENYDI CTEMLQSSTA 600
IQVEAGAERR DIVIRLPNLH NDSVVSLEEI DKNLKSLERC QSLEEIQRLY EAGDYKAVVH 660
LLRPTLCTSG FDRAKHLEFM TSIPERPAQL LLLQDSLLRL KDYRQCFECS DVALNEAVQQ 720
MVNSGEAAAK EEWVATVTQL LMGIEQALSA DSSGSILKVS SSTTGLVRLT NNLIQVIDCS 780
MAVQEEAKEP HVSSVLPWII LHRIIWQEED TFHSLCHQQQ LQNPAEEGMS ETPMLPSSLM 840
LLNTAHEYLG RRSWCCNSDG ALLRFYVRVL QKELAASTSE DTHPYKEELE TALEQCFYCL 900
YSFPSKKSKA RYLEEHSAQQ VDLIWEDALF MFEYFKPKTL PEFDSYKTST VSADLANLLK 960
RIATIVPRTE RPALSLDKVS AYIEGTSTEV PCLPEGADPS PPVVNELYYL LADYHFKNKE 1020
QSKAIKFYMH DICICPNRFD SWAGMALARA SRIQDKLNSN ELKSDGPIWK HATPVLNCFR 1080
RALEIDSSNL SLWIEYGTMS YALHSFASRQ LKQWRGELPP ELVQQMEGRR DSMLETAKHC 1140
FTSAARCEGD GDEEEWLIHY MLGKVAEKQQ QPPTVYLLHY RQAGHYLHEE AARYPKKIHY 1200
HNPPELAMEA LEVYFRLHAS ILKLLGKPDS GVGAEVLVNF MKEAAEGPFA RGEEKNTPKA 1260
SEKEKACLVD EDSHSSAGTL PGPGASLPSS SGPDRSQDST AVALSDSSST QDFFNEPTSL 1320
LEGSRKSYTE KRLPILSSQA GATGKDLQGA TEERGKNEES LESTEGFRAA EQGVQKPAAE 1380
TPASACIPGK PSASTPTLWD GKKRGDLPGE PVAFPQGLPA GAEEQRQFLT EQCIASFRLC 1440
LSRFPQHYKS LYRLAFLYTY SKTHRNLQWA RDVLLGSSIP WQQLQHMPAQ GLFCERNKTN 1500
FFNGIWRIPV DEIDRPGSFA WHMNRSIVLL LKVLAQLRDH STLLKVSSML QRTPDQGKKY 1560
LRDADRQVLA QRAFILTVKV LEDTLSELAE GSERPGPKVC GLPGARMTTD VSHKASPEDG 1620
QEGLPQPKKP PLADGSGPGP EPGGKVGLLN HRPVAMDAGD SADQSGERKD KESPRAGPTE 1680
PMDTSEATVC HSDLERTPPL LPGRPARDRG PESRPTELSL EELSISARQQ PTPLTPAQPA 1740
PAPAPATTTG TRAGGHPEEP LSRLSRKRKL LEDTESGKTL LLDAYRVWQQ GQKGVAYDLG 1800
RVERIMSETY MLIKQVDEEA ALEQAVKFCQ VHLGAAAQRQ ASGDTPTTPK HPKDSRENFF 1860
PVTVVPTAPD PVPADSVQRP SDAHTKPRPA LAAATTIITC PPSASASTLD QSKDPGPPRP 1920
HRPEATPSMA SLGPEGEELA RVAEGTSFPP QEPRHSPQVK MAPTSSPAEP HCWPAEAALG 1980
TGAEPTCSQE GKLRPEPRRD GEAQEAASET QPLSSPPTAA SSKAPSSGSA QPPEGHPGKP 2040
EPSRAKSRPL PNMPKLVIPS AATKFPPEIT VTPPTPTLLS PKGSISEETK QKLKSAILSA 2100
QSAANVRKES LCQPALEVLE TSSQESSLES ETDEDDDYMD I 2141 
Gene Ontology
 GO:0016235; C:aggresome; IDA:HPA.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR015134; MEF2_binding.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF09047; MEF2_binding 
SMART
 SM00028; TPR 
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS