CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030936
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GPI ethanolamine phosphate transferase 2 
Protein Synonyms/Alias
 cDNA FLJ54013, highly similar to GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) 
Gene Name
 PIGG 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
249ENVPSYEKDPGFEQFubiquitination[1, 2, 3]
257DPGFEQFKMSERLHGubiquitination[1, 2, 3]
285VLFNLGSKVLRQYLDubiquitination[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 341 AA 
Protein Sequence
MTGSLPGFVD VIRNLNSPAL LEDSVIRQAK AAGKRIVFYG DETWVKLFPK HFVEYDGTTS 60
FFVSDYTEVD NNVTRHLDKV LKRGDWDILI LHYLGLDHIG HISGPNSPLI GQKLSEMDSV 120
LMKIHTSLQS KERETPLPNL LVLCGDHGMS ETGSHGASST EEVNTPLILI SSAFERKPGD 180
IRHPKHVQQT DVAATLAIAL GLPIPKDSVG SLLFPVVEGR PMREQLRFLH LNTVQLSKLL 240
QENVPSYEKD PGFEQFKMSE RLHGNWIRLY LEEKHSEVLF NLGSKVLRQY LDALKTLSLS 300
LSAQVAQFSP CSCSASHRHC AERLSWKSHC HLLGFLCSFI W 341 
Gene Ontology
 GO:0016740; F:transferase activity; IEA:UniProtKB-KW. 
Interpro
 IPR017849; Alkaline_Pase-like_a/b/a.
 IPR017850; Alkaline_phosphatase_core.
 IPR002591; Phosphodiest/P_Trfase. 
Pfam
 PF01663; Phosphodiest 
SMART
  
PROSITE
  
PRINTS