CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020914
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alpha-soluble NSF attachment protein 
Protein Synonyms/Alias
 SNAP-alpha; N-ethylmaleimide-sensitive factor attachment protein alpha 
Gene Name
 Napa 
Gene Synonyms/Alias
 Snapa 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
6**MDNSGKQAEAMALubiquitination[1]
22AEAERKVKNSQSFFSubiquitination[1]
167SANKCLLKVAGYAAQubiquitination[1]
203PLLKYSAKDYFFKAAubiquitination[1]
227NAKLAVQKYEELFPAubiquitination[1]
285TMLLRIKKTIQGDEEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; ER-Golgi transport; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MDNSGKQAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN MFKMAKNWSA 60
AGNAFCQAAQ LHLQLQSKHD AATCFVDAGN AFKKADPQEA INCLMRAIEI YTDMGRFTIA 120
AKHHISIAEI YETELVDVEK AIAHYEQSAD YYKGEESNSS ANKCLLKVAG YAAQLEQYQK 180
AIDIYEQVGT SAMDSPLLKY SAKDYFFKAA LCHFCIDMLN AKLAVQKYEE LFPAFSDSRE 240
CKLMKKLLEA HEEQNVDSYT EAVKEYDSIS RLDQWLTTML LRIKKTIQGD EEDLR 295 
Gene Ontology
 GO:0070044; C:synaptobrevin 2-SNAP-25-syntaxin-1a complex; IDA:MGI.
 GO:0019905; F:syntaxin binding; IDA:MGI.
 GO:0045176; P:apical protein localization; IMP:MGI.
 GO:0007420; P:brain development; IMP:MGI.
 GO:0006886; P:intracellular protein transport; IMP:MGI.
 GO:0030182; P:neuron differentiation; IMP:MGI.
 GO:0010807; P:regulation of synaptic vesicle priming; IGI:MGI.
 GO:0035494; P:SNARE complex disassembly; IGI:MGI.
 GO:0035249; P:synaptic transmission, glutamatergic; IGI:MGI. 
Interpro
 IPR000744; NSF_attach.
 IPR011990; TPR-like_helical. 
Pfam
  
SMART
  
PROSITE
  
PRINTS
 PR00448; NSFATTACHMNT.