UniProt Accession

 CLD7_HUMAN; O95471; B2R9X7; D3DTP0; Q6IPN3; Q7Z4Y7; Q9BVN0 

Genbank Protein ID

 AJ011497; AK313958; BT006829; AC003688; CH471108; CH471108; BC001055; BC071844; AF093823 

Genbank Nucleotide ID

 CAA09626.1; BAG36674.1; AAP35475.1; EAW90228.1; EAW90229.1; AAH01055.1; AAH71844.1; AAP97219.1 

Protein Name

 Claudin-7 

Protein Synonyms/Alias

 CLDN-7 

Gene Name

 CLDN7 

Gene Synonyms/Alias

 CEPTRL2; CPETRL2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
203	RVPRSYPKSNSSKEY	ubiquitination	[1]
208	YPKSNSSKEYV****	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity). 

Sequence Annotation

 REGION 210 211 Interactions with TJP1, TJP2 and TJP3 (By  

Keyword

 Alternative splicing; Cell junction; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Tight junction; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 211 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; TAS:ProtInc.
 GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005923; C:tight junction; ISS:UniProtKB.
 GO:0042802; F:identical protein binding; ISS:UniProtKB.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB. 

Interpro

 IPR006187; Claudin.
 IPR003552; Claudin7.
 IPR017974; Claudin_CS.
 IPR004031; PMP22/EMP/MP20/Claudin. 

Pfam

 PF00822; PMP22_Claudin 

SMART

  

PROSITE

 PS01346; CLAUDIN 

PRINTS

 PR01077; CLAUDIN.
 PR01381; CLAUDIN7.