| Tag | Content |
|---|
| CPLM ID | CPLM-017195 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Reticulon-1 |
Protein Synonyms/Alias | Neuroendocrine-specific protein |
Gene Name | Rtn1 |
Gene Synonyms/Alias | Nsp |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 190 | ADPLDQMKAEAYKYI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells (By similarity). |
Sequence Annotation | DOMAIN 593 780 Reticulon.
MOD_RES 70 70 Phosphoserine.
MOD_RES 92 92 Phosphoserine.
MOD_RES 350 350 Phosphoserine.
MOD_RES 352 352 Phosphoserine.
MOD_RES 487 487 Phosphoserine (By similarity). |
Keyword | Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 780 AA |
Protein Sequence | MAAPPDLQDE PLSLGSPGSQ WFGGRGDGED EATAVMGARP AQQDGEPAWG SGAGAGVTSS 60
RELCSGPARS PPVAMETAST GMAAVPDALD HSPSSTLKDG EGACYTSLIS DVCYPPREDS 120
AYFTGILQKE NGHITTSESP EEPETPGPSL PEVPGMEPQG LLSSDSGIEM TPAESTEVNK 180
ILADPLDQMK AEAYKYIDIT RPQEAKGQEE QHPGLEDKDL DFKDKDTEVS TKAEGVRAPN 240
QPAPVEGKLI KDHLFEESTF APYIDELSDE QHRVSLVTAP VKITLTEIEP PLMTATQETI 300
PEKQDLCLKP SPDTVPTVTV SEPEDDSPGS VTPPSSGTEP SAAESQGKGS VSEDELIAAI 360
KEAKGLSYET TESPRPVGQV ADKPKTKTRS GLPTIPSPLD QEASSAESGD SEIELVSEDP 420
MASEDALPSG YVSFGHVSGP PPSPASPSIQ YSILREEREA ELDSELIIES CDASSASEES 480
PKREQDSPPM KPGALDAIRE ETGSRATEER APSHQGPVEP DPMLSFAPAA ALQSRPEPSS 540
GDGASVPEPP RSQQQKPEEE AVSSSQSPTA TEIPGPLGSG LMPPLPFFNK QKAIDLLYWR 600
DIKQTGIVFG SFLLLLFSLT QFSVVSVVAY LALAALSATI SFRIYKSVLQ AVQKTDEGHP 660
FKAYLELEIT LSQEQIQKYT DCLQLYVNST LKELRRLFLV QDLVDSLKFA VLMWLLTYVG 720
ALFNGLTLLL MAVVSMFTLP VVYVKHQAQV DQYLGLVRTH INTVVAKIQA KIPGAKRHAE 780 |
Gene Ontology | GO:0005783; C:endoplasmic reticulum; IDA:MGI. GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0030182; P:neuron differentiation; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |