CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039758
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 DEP domain-containing protein 1B 
Protein Synonyms/Alias
  
Gene Name
 DEPDC1B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
62NHVIEDIKGKWGEEDubiquitination[1]
64VIEDIKGKWGEEDFEubiquitination[1]
427LLMWALKKPFQPFQRubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MPLRKHRCRF KSYEHCFTAA EAVDWLHELL RCSQNFGPEV TRKQTVQLLK KFLKNHVIED 60
IKGKWGEEDF EDNRHLYRFP PSSPLKPYPK KPPNQKDVIK FPEWNDLPPG TSQENIPVRP 120
VVMNSEMWYK RHSIAIGEVP ACRLVHRRQL TEANVEEIWK SMTLSYLQKI LGLDSLEEVL 180
DVKLVNSKFI IHNVYSVSKQ GVVILDDKSK ELPHWVLSAM KCLANWPNCS DLKQPMYLGF 240
EKDVFKTIAD YYGHLKEPLL TFHLFDAFVS VLGLLQKEKV AVEAFQICCL LLPPENRRKL 300
QLLMRMMARI CLNKEMPPLC DGFGTRTLMV QTFSRCILCS KDEVDLDELL AARLVTFLMD 360
NYQEILKVPL ALQTSIEERV AHLRRVQFQK SYPEVYQERF PTPESAALLF PEKPKPKPQL 420
LMWALKKPFQ PFQRTRSFRM 440 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro. 
Interpro
 IPR000591; DEP_dom.
 IPR008936; Rho_GTPase_activation_prot.
 IPR000198; RhoGAP_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00610; DEP
 PF00620; RhoGAP 
SMART
 SM00049; DEP 
PROSITE
 PS50186; DEP
 PS50238; RHOGAP 
PRINTS