UniProt Accession

 E9PHH9_HUMAN; E9PHH9 

Genbank Protein ID

 AL160282 

Genbank Nucleotide ID

  

Protein Name

 DNA-directed RNA polymerase III subunit RPC3 

Protein Synonyms/Alias

  

Gene Name

 POLR3C 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
51	GTSLDQVKKALCVLV	ubiquitination	[1]
192	KDMYLVPKLSLIGKG	ubiquitination	[1, 2]
225	PKYTTDNKEPIPDDG	ubiquitination	[1, 3]
378	QKKHIEQKQVEDFAM	ubiquitination	[1]
389	DFAMIPAKEAKDMLY	ubiquitination	[1]
392	MIPAKEAKDMLYKML	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 411 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR013197; RNA_pol_III_RPC82-rel_HTH.
 IPR008806; RNA_pol_III_Rpc82_C. 

Pfam

 PF08221; HTH_9
 PF05645; RNA_pol_Rpc82 

SMART

  

PROSITE

  

PRINTS