| Tag | Content |
|---|
| CPLM ID | CPLM-016801 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ligand-dependent nuclear receptor-interacting factor 1 |
Protein Synonyms/Alias | |
Gene Name | Lrif1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 39 | TIGSDGKKLLQLLPI | ubiquitination | [1] | | 307 | SSNNVATKVLNTFVG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Represses the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA). This repression may occur through direct recruitment of histone deacetylases (By similarity). |
Sequence Annotation | MOTIF 612 615 Nuclear localization signal (By
MOD_RES 391 391 Phosphoserine (By similarity).
MOD_RES 584 584 Phosphoserine (By similarity).
MOD_RES 717 717 Phosphothreonine (By similarity). |
Keyword | Alternative splicing; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 755 AA |
Protein Sequence | MSNSLQSVIL KTAEEKSGSR CISGCMYQVV PTIGSDGKKL LQLLPISKSS GNLIPVVQSP 60
VMSHGLKANT EKPVQVTFQT QISSSSTSAS VQLPVFQPAN TTKCFFTGAI DTTGKDRVTS 120
VRTGNFTPPV SNIQNHGVKI HKLTRQTFTI PPSTQNDSSH FIFNTPSLLP NVNSSILPSG 180
NHLKIPAHAE VKSVLASSLP PLVQQKILGT ATTSTSGTVE ASQIPTVVYV HPVNSVKFVV 240
TKKTQTIYPK PVTFNTLQIP PNVATETQLK GGQHPQAAPV NSIFQEYLQP GIPCIIPVKS 300
SNNVATKVLN TFVGRKNLGD NTIDTPLLNT NSSGRTHSVS EPIKDNALIM FNGKVWLNEK 360
GTCGLPSKID QQNSVSSDIP LKDSSQLVSS SIVTEISREI LNSVLVKSKS FQLKTKSLSN 420
SQLASMANLR AEKNEKVERP SFSVTNPHTM NQSTHCLKQS KTVFINPVFP DGFRTGQNAP 480
RKGNLVQNIE KICSSVDAAT VTSQQCVFRD QESQTQYEMA SIVKKEIQEK GNNKKYSQGS 540
HTNIKASCLK NDAEFKKLFG LTKDLRVCLT RIPDHLSSGK SFNSFNSLMK SSSYKDANIV 600
VKKEEKKQSF SKKRKAETMK MGNTKKIKIE NADDTVMSIM NGTDVASSQP LSSILPTSDI 660
SQHNIVTSHS TTREDKRTEA EHCSHEKQEK GTLSSSTSFE QSTFLNKNFM EDIFPVTPPE 720
LEETIRDEKI RRLKQILREK EAALEELRKK MYQKQ 755 |
Gene Ontology | GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |