UniProt Accession

 B0YJ28_HUMAN; B0YJ28 

Genbank Protein ID

 EF444989 

Genbank Nucleotide ID

 ACA06006.1 

Protein Name

 Interleukin-18 

Protein Synonyms/Alias

  

Gene Name

 IL18 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
115	STLSCENKIISFKEM	ubiquitination	[1]
120	ENKIISFKEMNPPDN	ubiquitination	[1]
132	PDNIKDTKSDIIFFQ	ubiquitination	[1]
171	EKERDLFKLILKKED	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Cytokine. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 193 AA 

Protein Sequence

Gene Ontology

 GO:0005615; C:extracellular space; IEA:UniProtKB-KW. 

Interpro

 IPR008996; Cytokine_IL1-like.
 IPR000975; Interleukin_1.
 IPR015529; Interleukin_18. 

Pfam

 PF00340; IL1 

SMART

 SM00125; IL1 

PROSITE

  

PRINTS

 PR01933; INTRLEUKIN18.