CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009576
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L23 
Protein Synonyms/Alias
  
Gene Name
 Rpl23 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
13RGGSSGAKFRISLGLacetylation[1]
66DMVMATVKKGKPELRubiquitination[2]
113VNNKGEMKGSAITGPubiquitination[2]
123AITGPVAKECADLWPacetylation[3]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
 MOD_RES 17 17 Phosphoserine (By similarity).
 MOD_RES 38 38 Phosphotyrosine (By similarity).  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 140 AA 
Protein Sequence
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM 60
VMATVKKGKP ELRKKVHPAV VIRQRKSYRR KDGVFLYFED NAGVIVNNKG EMKGSAITGP 120
VAKECADLWP RIASNAGSIA 140 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; IEA:Compara.
 GO:0022626; C:cytosolic ribosome; ISA:MGI.
 GO:0005730; C:nucleolus; IDA:MGI.
 GO:0003735; F:structural constituent of ribosome; ISA:MGI.
 GO:0006412; P:translation; ISA:MGI. 
Interpro
 IPR019972; Ribosomal_L14_CS.
 IPR023571; Ribosomal_L14_dom.
 IPR000218; Ribosomal_L14b/L23e. 
Pfam
 PF00238; Ribosomal_L14 
SMART
  
PROSITE
 PS00049; RIBOSOMAL_L14 
PRINTS