CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022587
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UV radiation resistance-associated gene protein 
Protein Synonyms/Alias
 p63 
Gene Name
 UVRAG 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
87FYRSEVIKNSLNPTWubiquitination[1]
176KGYSNAQKTILLQVDubiquitination[1]
267REVALLHKQQIALQDubiquitination[1]
396KGSRSTIKDNINDKLubiquitination[1]
402IKDNINDKLTEKEREubiquitination[1]
455RQTLPNLKNFMEHGLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 44 128 C2.
 MOD_RES 498 498 Phosphoserine.
 MOD_RES 518 518 Phosphothreonine.
 MOD_RES 571 571 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Endosome; Lysosome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 699 AA 
Protein Sequence
MSASASVGGP VPQPPPGPAA ALPPGSAARA LHVELPSQQR RLRHLRNIAA RNIVNRNGHQ 60
LLDTYFTLHL CSTEKIYKEF YRSEVIKNSL NPTWRSLDFG IMPDRLDTSV SCFVVKIWGG 120
KENIYQLLIE WKVCLDGLKY LGQQIHARNQ NEIIFGLNDG YYGAPFEHKG YSNAQKTILL 180
QVDQNCVRNS YDVFSLLRLH RAQCAIKQTQ VTVQKIGKEI EEKLRLTSTS NELKKKSECL 240
QLKILVLQNE LERQKKALGR EVALLHKQQI ALQDKGSAFS AEHLKLQLQK ESLNELRKEC 300
TAKRELFLKT NAQLTIRCRQ LLSELSYIYP IDLNEHKDYF VCGVKLPNSE DFQAKDDGSI 360
AVALGYTAHL VSMISFFLQV PLRYPIIHKG SRSTIKDNIN DKLTEKEREF PLYPKGGEKL 420
QFDYGVYLLN KNIAQLRYQH GLGTPDLRQT LPNLKNFMEH GLMVRCDRHH TSSAIPVPKR 480
QSSIFGGADV GFSGGIPSPD KGHRKRASSE NERLQYKTPP PSYNSALAQP VTTVPSMGET 540
ERKITSLSSS LDTSLDFSKE NKKKGEDLVG SLNGGHANVH PSQEQGEALS GHRATVNGTL 600
LPSEQAGSAS VQLPGEFHPV SEAELCCTVE QAEEIIGLEA TGFASGDQLE AFNCIPVDSA 660
VAVECDEQVL GEFEEFSRRI YALNENVSSF RRPRRSSDK 699 
Gene Ontology
 GO:0005769; C:early endosome; IDA:UniProtKB.
 GO:0005770; C:late endosome; IDA:UniProtKB.
 GO:0005764; C:lysosome; IDA:UniProtKB.
 GO:0043234; C:protein complex; IEA:Compara.
 GO:0006281; P:DNA repair; TAS:ProtInc.
 GO:0010508; P:positive regulation of autophagy; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018791; UV_resistance/autophagy_Atg14. 
Pfam
 PF10186; Atg14
 PF00168; C2 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS