CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037552
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ester hydrolase C11orf54 
Protein Synonyms/Alias
  
Gene Name
 C11orf54 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
75LLPLVNQKKVYDLNKubiquitination[1, 2, 3]
76LPLVNQKKVYDLNKIubiquitination[4]
82KKVYDLNKIAKEIKLacetylation[5]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 171 AA 
Protein Sequence
MACAEFSFHV PSLEELAGVM QKGLKDNFAD VQVSVVDCPD LTKEPFTFPV KGICGKTRIA 60
EVGGVPYLLP LVNQKKVYDL NKIAKEIKLP GAFILGAGAG PFQTLGFNSE FMPVIQTESE 120
HKPPVNGSYF AHVNPADGGC LLEKYSEKCH DFQCALLANL FASEGQPGKV I 171 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro. 
Interpro
 IPR015021; DUF1907. 
Pfam
 PF08925; DUF1907 
SMART
  
PROSITE
  
PRINTS