| Tag | Content |
|---|
| CPLM ID | CPLM-003293 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Biotin carboxyl carrier protein of acetyl-CoA carboxylase |
Protein Synonyms/Alias | BCCP |
Gene Name | accB |
Gene Synonyms/Alias | fabE; b3255; JW3223 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 100 | RTPSPDAKAFIEVGQ | acetylation | [1] | | 131 | MNQIEADKSGTVKAI | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. |
Sequence Annotation | DOMAIN 81 155 Biotinyl-binding.
MOD_RES 122 122 N6-biotinyllysine. |
Keyword | 3D-structure; Biotin; Complete proteome; Direct protein sequencing; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 156 AA |
Protein Sequence | MDIRKIKKLI ELVEESGISE LEISEGEESV RISRAAPAAS FPVMQQAYAA PMMQQPAQSN 60
AAAPATVPSM EAPAAAEISG HIVRSPMVGT FYRTPSPDAK AFIEVGQKVN VGDTLCIVEA 120
MKMMNQIEAD KSGTVKAILV ESGQPVEFDE PLVVIE 156 |
Gene Ontology | GO:0009317; C:acetyl-CoA carboxylase complex; IDA:EcoCyc. GO:0003989; F:acetyl-CoA carboxylase activity; IMP:EcoliWiki. GO:0009374; F:biotin binding; IDA:EcoCyc. GO:0006633; P:fatty acid biosynthetic process; IDA:EcoCyc. |
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