| Tag | Content |
|---|
| CPLM ID | CPLM-015929 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Low-density lipoprotein receptor-related protein 10 |
Protein Synonyms/Alias | LRP-10 |
Gene Name | LRP10 |
Gene Synonyms/Alias | MSTP087; SP220; UNQ389/PRO724 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 619 | QAPPLPIKAPLPSAS | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver (By similarity). |
Sequence Annotation | DOMAIN 28 136 CUB 1.
DOMAIN 139 175 LDL-receptor class A 1.
DOMAIN 192 305 CUB 2.
DOMAIN 307 354 LDL-receptor class A 2.
DOMAIN 355 397 LDL-receptor class A 3.
DOMAIN 398 434 LDL-receptor class A 4.
MOD_RES 596 596 Phosphothreonine.
CARBOHYD 56 56 N-linked (GlcNAc...) (Potential).
CARBOHYD 111 111 N-linked (GlcNAc...) (Potential).
CARBOHYD 193 193 N-linked (GlcNAc...) (Potential).
CARBOHYD 299 299 N-linked (GlcNAc...) (Potential).
DISULFID 28 57 By similarity.
DISULFID 80 98 By similarity.
DISULFID 140 152 By similarity.
DISULFID 147 165 By similarity.
DISULFID 159 174 By similarity.
DISULFID 192 220 By similarity.
DISULFID 308 331 By similarity.
DISULFID 315 344 By similarity.
DISULFID 338 353 By similarity.
DISULFID 356 374 By similarity.
DISULFID 363 387 By similarity.
DISULFID 381 396 By similarity.
DISULFID 399 411 By similarity.
DISULFID 406 424 By similarity.
DISULFID 418 433 By similarity. |
Keyword | Alternative splicing; Coated pit; Complete proteome; Disulfide bond; Endocytosis; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 713 AA |
Protein Sequence | MLLATLLLLL LGGALAHPDR IIFPNHACED PPAVLLEVQG TLQRPLVRDS RTSPANCTWL 60
ILGSKEQTVT IRFQKLHLAC GSERLTLRSP LQPLISLCEA PPSPLQLPGG NVTITYSYAG 120
ARAPMGQGFL LSYSQDWLMC LQEEFQCLNH RCVSAVQRCD GVDACGDGSD EAGCSSDPFP 180
GLTPRPVPSL PCNVTLEDFY GVFSSPGYTH LASVSHPQSC HWLLDPHDGR RLAVRFTALD 240
LGFGDAVHVY DGPGPPESSR LLRSLTHFSN GKAVTVETLS GQAVVSYHTV AWSNGRGFNA 300
TYHVRGYCLP WDRPCGLGSG LGAGEGLGER CYSEAQRCDG SWDCADGTDE EDCPGCPPGH 360
FPCGAAGTSG ATACYLPADR CNYQTFCADG ADERRCRHCQ PGNFRCRDEK CVYETWVCDG 420
QPDCADGSDE WDCSYVLPRK VITAAVIGSL VCGLLLVIAL GCTCKLYAIR TQEYSIFAPL 480
SRMEAEIVQQ QAPPSYGQLI AQGAIPPVED FPTENPNDNS VLGNLRSLLQ ILRQDMTPGG 540
GPGARRRQRG RLMRRLVRRL RRWGLLPRTN TPARASEARS QVTPSAAPLE ALDGGTGPAR 600
EGGAVGGQDG EQAPPLPIKA PLPSASTSPA PTTVPEAPGP LPSLPLEPSL LSGVVQALRG 660
RLLPSLGPPG PTRSPPGPHT AVLALEDEDD VLLVPLAEPG VWVAEAEDEP LLT 713 |
Gene Ontology | GO:0005905; C:coated pit; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005041; F:low-density lipoprotein receptor activity; IEA:Compara. GO:0048839; P:inner ear development; IEA:Compara. GO:0006629; P:lipid metabolic process; IEA:Compara. GO:0006869; P:lipid transport; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |