CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006249
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SKG6 
Protein Synonyms/Alias
 Suppressor of lethality of KEX2-GAS1 double null mutant 6 
Gene Name
 SKG6 
Gene Synonyms/Alias
 YHR149C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
144SQQDFMEKTLQQPPSubiquitination[1]
162VGSMHSSKYNVRSATubiquitination[1]
210EDGLGGYKVAAESRNubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 May be involved in the polarity establishment process. Suppresses the lethality of KEX2-GAS1 double null mutant when overexpressed. 
Sequence Annotation
 MOD_RES 137 137 Phosphoserine.
 MOD_RES 191 191 Phosphoserine.
 MOD_RES 193 193 Phosphoserine.
 MOD_RES 219 219 Phosphoserine.
 MOD_RES 221 221 Phosphothreonine.
 MOD_RES 222 222 Phosphoserine.
 MOD_RES 251 251 Phosphoserine.
 MOD_RES 369 369 Phosphoserine.
 MOD_RES 672 672 Phosphoserine.
 MOD_RES 717 717 Phosphoserine.  
Keyword
 Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 734 AA 
Protein Sequence
MYHTHMHESL ISVTSTVSVS DASYAYARLT RRDDSDSSSS SASSTKNSKS AECTGSKQQC 60
QLPTDSSHST SVTVGVAVAV PVGVIIIVLA VILCIVYRRS KKEAEEDNDP DFEGDSEFLP 120
TMKDYSPGIN HLYSSDSQQD FMEKTLQQPP SDPFVGSMHS SKYNVRSATP PAIGRSWYVD 180
PFQLPQESND SNSLRDFAMR VQEDGLGGYK VAAESRNASQ TSLHPDNFSN CTPIRASSRF 240
QESESFRSHG SPIHNNQLSR GSATEGANKQ FTFPNEDNDS SSVSEEAEVL NESNESASND 300
AFEFELDNSS EKTHERNLRF GKDDDNYELQ DIREAEHMND RSSSKSQDDD YYVSLLSPNE 360
EEDIKRMKSI YQVYLDRAKT MKKEEDKADN ANDISQEENR VDNIVQNPLP SIKINNNDNI 420
DNNEVPEAKH LVKEALPLNN TNLAEYGPEM AQSQKQYPVQ DTLTVNDTEA APSNRIASSI 480
YSEAIQPLNY QDQYQQQEQS PVYNGHTQYP GNGYSGNPQQ QGYTAQFVQN PQWYGVPTPQ 540
QQQHNHPQTL ETIGELPTPA YLAQSASSHS LTSFKRPNKQ QLLQLQTARL NGTALNPVDH 600
PEMFYSPTND AYYAPQQQGQ YMKFNENGAV PSPYQLRQSV VMTNPSDLTA KPSYKPAGSF 660
RSVSATNSRN NSLTTQNNIY LQQQQQQLYN SRVSGILEET DVVQPPSVGG ILPHSGSQDD 720
LRKQLGSSHN YTVN 734 
Gene Ontology
 GO:0005938; C:cell cortex; IDA:SGD.
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0000131; C:incipient cellular bud site; IDA:SGD.
 GO:0016021; C:integral to membrane; IDA:SGD. 
Interpro
 IPR014805; SKG6/AXL2_alpha-helix_TM. 
Pfam
 PF08693; SKG6 
SMART
  
PROSITE
  
PRINTS