CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029790
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Trophinin 
Protein Synonyms/Alias
  
Gene Name
 TRO 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
189LITDEFVKQKYLEYKubiquitination[1, 2]
191TDEFVKQKYLEYKRVubiquitination[1, 2]
196KQKYLEYKRVPNSRPubiquitination[1]
220RSYHETSKMKVLKFAubiquitination[3]
225TSKMKVLKFACRVQKubiquitination[1]
236RVQKKDPKDWAVQYRubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1034 AA 
Protein Sequence
MDRRNDYGYR VPLFQSKHLN GDERSGSNYR RIPWGRRPAP PRDVAILQER ANKLVKYLLV 60
KDQTKIPIKR SDMLRDVIQE YDEYFPEIIE RASYTLEKMF RVNLKEIDKQ SSLYILISTQ 120
ESSAGILGTT KDTPKLGLLM VILSVIFMNG NKASEAVIWE VLRKLGLRPG VRHSLFGEVR 180
KLITDEFVKQ KYLEYKRVPN SRPPEYEFFW GLRSYHETSK MKVLKFACRV QKKDPKDWAV 240
QYREAVEMEV QAAAVAVAEA EARAEARAQM GIGEEAVAGP WNWDDMDIDC LTREELGDDA 300
QAWSRFSFEI EARAQENADA STNVNFSRGA STRAGFSDGA SISFNGAPSS SGGFSGGPGI 360
TFGVAPSTSA SFSNTASISF GGTLSTSSSF SSAASISFGC AHSTSTSFSS EASISFGGMP 420
CTSASFSGGV SSSFSGPLST SATFSGGASS GFGGTLSTTA GFSGVLSTST SFGSAPTTST 480
VFSSALSTST GFGGILSTSV CFGGSPSSSG SFGGTLSTSI CFGGSPCTST GFGGTLSTSV 540
SFGGSSSTSA NFGGTLSTSI CFDGSPSTGA GFGGALNTSA SFGSVLNTST GFGGAMSTSA 600
DFGGTLSTSV CFGGSPGTSV SFGSALNTNA GYGGAVSTNT DFGGTLSTSV CFGGSPSTSA 660
GFGGALNTNA SFGCAVSTSA SFSGAVSTSA CFSGAPITNP GFGGAFSTSA GFGGALSTAA 720
DFGGTPSNSI GFGAAPSTSV SFGGAHGTSL CFGGAPSTSL CFGSASNTNL CFGGPPSTSA 780
CFSGATSPSF CDGPSTSTGF SFGNGLSTNA GFGGGLNTSA GFGGGLGTSA GFSGGLSTSS 840
GFDGGLGTSA GFGGGPGTST GFGGGLGTSA GFSGGLGTSA GFGGGLVTSD GFGGGLGTNA 900
SFGSTLGTSA GFSGGLSTSD GFGSRPNASF DRGLSTIIGF GSGSNTSTGF TGEPSTSTGF 960
SSGPSSIVGF SGGPSTGVGF CSGPSTSGFS GGPSTGAGFG GGPNTGAGFG GGPSTSAGFG 1020
SGAASLGACG FSYG 1034 
Gene Ontology
  
Interpro
 IPR002190; MAGE. 
Pfam
 PF01454; MAGE 
SMART
  
PROSITE
 PS50838; MAGE 
PRINTS