| Tag | Content |
|---|
| CPLM ID | CPLM-011296 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Inositol monophosphatase 2 |
Protein Synonyms/Alias | IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2 |
Gene Name | INM2 |
Gene Synonyms/Alias | IMP2; YDR287W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 161 | KRPLILQKSLIALEG | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and involved in the inositol cycle of calcium signaling. |
Sequence Annotation | REGION 96 99 Substrate binding (By similarity).
METAL 75 75 Magnesium 1 (By similarity).
METAL 94 94 Magnesium 1 (By similarity).
METAL 94 94 Magnesium 2 (By similarity).
METAL 96 96 Magnesium 1; via carbonyl oxygen (By
METAL 97 97 Magnesium 2 (By similarity).
METAL 231 231 Magnesium 2 (By similarity).
BINDING 75 75 Substrate (By similarity).
BINDING 231 231 Substrate (By similarity). |
Keyword | Complete proteome; Hydrolase; Lithium; Magnesium; Metal-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 292 AA |
Protein Sequence | MVLTRQVLEE VENTFIELLR SKIGPLVKSH AGTNFCSYDD KANGVDLVTA LDKQIESIIK 60
ENLTAKYPSF KFIGEETYVK GVTKITNGPT FIVDPIDGTT NFIHGYPYSC TSLGLAEMGK 120
PVVGVVFNPH LNQLFHASKG NGAFLNDQEI KVSKRPLILQ KSLIALEGGS ERTEGSQGNF 180
DKKMNTYKNL LSESGAFVHG FRSAGSAAMN ICYVASGMLD AYWEGGCWAW DVCAGWCILE 240
EAGGIMVGGN CGEWNIPLDR RCYLAIRGGC ESMEQKRFAE SFWPHVAGEL EY 292 |
Gene Ontology | GO:0008934; F:inositol monophosphate 1-phosphatase activity; IDA:SGD. GO:0052832; F:inositol monophosphate 3-phosphatase activity; IEA:EC. GO:0052833; F:inositol monophosphate 4-phosphatase activity; IEA:EC. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-UniPathway. GO:0046855; P:inositol phosphate dephosphorylation; IDA:SGD. GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |