| Tag | Content |
|---|
| CPLM ID | CPLM-014054 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial |
Protein Synonyms/Alias | |
Gene Name | Clpx |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 164 | VKLAFQQKPPPPPKK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP (By similarity). |
Sequence Annotation | ZN_FING 105 130 C4-type.
NP_BIND 293 300 ATP (Potential).
MOD_RES 437 437 N6-acetyllysine (By similarity).
MOD_RES 617 617 Phosphoserine (By similarity). |
Keyword | Acetylation; ATP-binding; Chaperone; Complete proteome; Metal-binding; Mitochondrion; Nucleotide-binding; Phosphoprotein; Reference proteome; Transit peptide; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 633 AA |
Protein Sequence | MSSCGACTCG AAAARLLTTS LTSAQRGISC GRIHVPVLGR LGTLDTQILR RAPLRTFSET 60
PAYFASKDGT NKDGSGDGNK KSVTEGSSKK SGSGNSGKGG NQLRCPKCGD LCTHVETFVS 120
STRFVKCEKC HHFFVVLSEA DSKKSIIKEP ESAAEAVKLA FQQKPPPPPK KIYNYLDKYV 180
VGQSFAKKVL SVAVYNHYKR IYNNIPANLR QQAEVEKQTS LTPRELEIRR REDEYRFTKL 240
LQIAGISPHG NALGASMQQQ GSQQMPQEKR GGEVLDSPHD DIKLEKSNIL LLGPTGSGKT 300
LLAQTLAKCL DVPFAICDCT TLTQAGYVGE DIESVIAKLL QDANYNVEKA QQGIVFLDEV 360
DKIGSVPGIH QLRDVGGEGV QQGLLKLLEG TIVNVPEKNS RKLRGETVQV DTTNILFVAS 420
GAFNGLDRII SRRKNEKYLG FGTPSNLGKG RRAAAAADLA NRSGESNTHQ DIEEKDRLLR 480
HVEARDLIEF GMIPEFVGRL PVVVPLHSLD EKTLVQILTE PRNAVIPQYQ ALFSMDKCEL 540
NVTEDALKAI ARLALERKTG ARGLRSIMEK LLLEPMFEVP NSDIVCVEVD KEVVEGKKEP 600
GYIRAPSKES SEEDYDSGVE EDGWPRQADA ANS 633 |
Gene Ontology | GO:0009841; C:mitochondrial endopeptidase Clp complex; IEA:Compara. GO:0005743; C:mitochondrial inner membrane; IEA:Compara. GO:0042645; C:mitochondrial nucleoid; IEA:Compara. GO:0005634; C:nucleus; IEA:Compara. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004176; F:ATP-dependent peptidase activity; IEA:Compara. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0016504; F:peptidase activator activity; IEA:Compara. GO:0006457; P:protein folding; IEA:InterPro. GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |