CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025841
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 2 (Facilitated glucose transporter), member 1 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
270THDLQEMKEESRQMMubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Membrane; Sugar transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 517 AA 
Protein Sequence
AGERRSHARR HPRTRRSQSH QRSAAMEPSS KKLTGRLMLA VGGAVLGSLQ FGYNTGVINA 60
PQKVIEEFYN QTWVHRYGES ILPTTLTTLW SLSVAIFSVG GMIGSFSVGL FVNRFGRRNS 120
MLMMNLLAFV SAVLMGFSKL GKSFEMLILG RFIIGVYCGL TTGFVPMYVG EVSPTALRGA 180
LGTLHQLGIV VGILIAQVFG LDSIMGNKDL WPLLLSIIFI PALLQCIVLP FCPESPRFLL 240
INRNEENRAK SVLKKLRGTA DVTHDLQEMK EESRQMMREK KVTILELFRS PAYRQPILIA 300
VVLQLSQQLS GINAVFYYST SIFEKAGVQQ PVYATIGSGI VNTAFTVVSL FVVERAGRRT 360
LHLIGLAGMA GCAILMTIAL ALLEQLPWMS YLSIVAIFGF VAFFEVGPGP IPWFIVAELF 420
SQGPRPAAIA VAGFSNWTSN FIVGMCFQYV EQLCGPYVFI IFTVLLVLFF IFTYFKVPET 480
KGRTFDEIAS GFRQGGASQS DKTPEELFHP LGADSQV 517 
Gene Ontology
 GO:0016323; C:basolateral plasma membrane; IEA:Compara.
 GO:0005901; C:caveola; IEA:Compara.
 GO:0005911; C:cell-cell junction; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0001939; C:female pronucleus; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0031982; C:vesicle; IEA:Compara.
 GO:0055056; F:D-glucose transmembrane transporter activity; IEA:Compara.
 GO:0033300; F:dehydroascorbic acid transporter activity; IEA:Compara.
 GO:0042910; F:xenobiotic transporter activity; IEA:Compara.
 GO:0042149; P:cellular response to glucose starvation; IEA:Compara.
 GO:0006970; P:response to osmotic stress; IEA:Compara. 
Interpro
 IPR002439; Glu_transpt_1.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR01190; GLUCTRSPORT1.
 PR00171; SUGRTRNSPORT.