CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040835
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptotagmin-like protein 4 
Protein Synonyms/Alias
  
Gene Name
 SYTL4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
123GDWFYDQKVNRFAYRubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 673 AA 
Protein Sequence
MSELLDLSFL SEEEKDLILS VLQRDEEVRK ADEKRIRRLK NELLEIKRKG AKRGSQHYSD 60
RTCARCQESL GRLSPKTNTC RGCNHLVCRD CRIQESNGTW RCKVCAKEIE LKKATGDWFY 120
DQKVNRFAYR TGSEIIRMSL RHKPAVSKRE TVGQSLLHQT QMGDIWPGRK IIQERQKEPS 180
SVLFEVPKLK SGKSALEAES ESLDSFTADS DSTSRRDSLD KSGLFPEWKK MSAPKSQVEK 240
ETQPGGQNVV FVDEGEMIFK KNTRKILRPS EYTKSVIDLR PEDVVHESGS LGDRSKSVPG 300
LNVDMVEEEE EEEDIDHLVK LHRQKLARSS MQSGSSMSTI GSMMSIYSEA GDFGNIFVTG 360
RIAFSLKYEQ QTQSLVVHVK ECHQLAYADE AKKRSNPYVK TYLLPDKSRQ GKRKTSIKRD 420
TINPLYDETL RYEIPESLLA QRTLQFSVWH HGRFGRNTFL GEAEIQMDSW KLDKKLDHCL 480
PLHGKISAES PTGLPSHKGE LVVSLKYIPA SKTPVGGDRK KSKGGEGGEL QVWIKEAKNL 540
TAAKAGGTSD SFVKGYLLPM RNKASKRKTP VMKKTLNPHY NHTFVYNGVR LEDLQHMCLE 600
LTVWDREPLA SNDFLGGVRL GVGTGISNGE VVDWMDSTGE EVSLWQKMRQ YPGSWAEGTL 660
QLRSSMAKQK LGL 673 
Gene Ontology
 GO:0005813; C:centrosome; IDA:HPA.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0008021; C:synaptic vesicle; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR010911; Rab-bd_domain.
 IPR001565; Synaptotagmin.
 IPR011011; Znf_FYVE_PHD.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF00168; C2 
SMART
 SM00239; C2
 SM00184; RING 
PROSITE
 PS50004; C2
 PS50916; RABBD 
PRINTS
 PR00399; SYNAPTOTAGMN.