CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018576
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein TBRG4 
Protein Synonyms/Alias
 Transforming growth factor beta regulator 4 
Gene Name
 Tbrg4 
Gene Synonyms/Alias
 Kiaa0948 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
617WQKSAYLKDKMRKAMacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 May play a role in cell cycle progression (By similarity). 
Sequence Annotation
 DOMAIN 560 618 RAP.  
Keyword
 Alternative splicing; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 630 AA 
Protein Sequence
MAVRLMKRCT CLLREATRLV PTVAPVGRLR LAGVSCKTLT SSVSSPSSGS LAELLGKEQV 60
FTPYPEHQEL DFLIEKASRP EQLLELLGSD HSLHHNHAAL ILIRLSYLLS EKPKEKALLA 120
EDARFQRLVK LVDSQITCVW HGTLVKLLRS LYTLVLPQIS KELQSVEQEV RWRLRRLKYK 180
HLVFLAESCA SFMKEQHSQE LLAELLMHLE RRWTEINDSR TLVTMMTMAG HLSESLMNHL 240
EDKCLELVEQ FGPDELRKVL VTLAAQSRRS VPLLRAISYH LVQKPFPMTK GMLLDLAYAY 300
GKLSFHQTQV SQRLAADLLP FIPSMTPGEV ARCAKSFAFL KWLNLPLFEA FTQHLLSRVQ 360
DVSLSHVCSV LLAFARLNFH PEQEEDQFFS MVHEKLDPVL GSLEPALQVD LVWALCVLQH 420
VHETELHTVL HPGLHARFLE SKSPKDQSTF QKLVHINTTA LLEHPEYKGP FLPASAVAPI 480
PSPSNKKMTP LQKELQETLK ALLGNTDKGS LEVATQYGWV LDAEVLLDAD GHFLPLRNFV 540
APHLAQPVGN QPLPPGAKRI AFLRWEFPNF NSRSKDLLGR FVLARRHVLA AGFLVVDVPY 600
YEWLDLKSEW QKSAYLKDKM RKAMAEELAK 630 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004672; F:protein kinase activity; IEA:InterPro.
 GO:0045333; P:cellular respiration; ISS:UniProtKB.
 GO:0006468; P:protein phosphorylation; IEA:GOC. 
Interpro
 IPR013579; FAST_2.
 IPR010622; FAST_Leu-rich.
 IPR013584; RAP. 
Pfam
 PF06743; FAST_1
 PF08368; FAST_2
 PF08373; RAP 
SMART
 SM00952; RAP 
PROSITE
 PS51286; RAP 
PRINTS