CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044313
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 NACHT, LRR and PYD domains-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 NLRP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
656KMSLQVIKENLPENVubiquitination[1]
1034LLEEIEEKNPQLIIDubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1059 AA 
Protein Sequence
MVSSAQMGFN LQALLEQLSQ DELSKFKYLI TTFSLAHELQ KIPHKEVDKA DGKQLVEILT 60
THCDSYWVEM ASLQVFEKMH RMDLSERAKD EVREAALKSF NKRKPLSLGI TRKERPPLDV 120
DEMLERFKTE AQETKGNVIC LGKEVFKGKK PDKDNRCRYI LKTKFREMWK SWPGDSKEVQ 180
VMAERYKMLI PFSNPRVLPG PFSYTVVLYG PAGLGKTTLA QKLMLDWAED NLIHKFKYAF 240
YLSCRELSRL GPCSFAELVF RDWPELQDDI PHILAQARKI LFVIDGFDEL GAAPGALIED 300
ICGDWEKKKP VPVLLGSLLN RVMLPKAALL VTTRPRALRD LRILAEEPIY IRVEGFLEED 360
RRAYFLRHFG DEDQAMRAFE LMRSNAALFQ LGSAPAVCWI VCTTLKLQME KGEDPVPTCL 420
TRTGLFLRFL CSRFPQGAQL RGALRTLSLL AAQGLWAQTS VLHREDLERL GVQESDLRLF 480
LDGDILRQDR VSKGCYSFIH LSFQQFLTAL FYTLEKEEEE DRDGHTWDIG DVQKLLSGVE 540
RLRNPDLIQA GYYSFGLANE KRAKELEATF GCRMSPDIKQ ELLRCDISCK GGHSTVTDLQ 600
ELLGCLYESQ EEELVKEVMA QFKEISLHLN AVDVVPSSFC VKHCRNLQKM SLQVIKENLP 660
ENVTASESDA EVERSQDDQH MLPFWTDLCS IFGSNKDLMG LAINDSFLSA SLVRILCEQI 720
ASDTCHLQRV VFKNISPADA HRNLCLALRG HKTVTYLTLQ GNDQDDMFPA LCEVLRHPEC 780
NLRYLGLVSC SATTQQWADL SLALEVNQSL TCVNLSDNEL LDEGAKLLYT TLRHPKCFLQ 840
RLSLENCHLT EANCKDLAAV LVVSRELTHL CLAKNPIGNT GVKFLCEGLR YPECKLQTLV 900
LWNCDITSDG CCDLTKLLQE KSSLLCLDLG LNHIGVKGMK FLCEALRKPL CNLRCLWLWG 960
CSIPPFSCED LCSALSCNQS LVTLDLGQNP LGSSGVKMLF ETLTCSSGTL RTLRLKIDDF 1020
NDELNKLLEE IEEKNPQLII DTEKHHPWAE RPSSHDFMI 1059 
Gene Ontology
  
Interpro
 IPR004020; DAPIN.
 IPR011029; DEATH-like_dom.
 IPR007111; NACHT_NTPase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02758; PYRIN 
SMART
  
PROSITE
 PS50824; DAPIN
 PS50837; NACHT 
PRINTS