CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011504
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytokinesis protein 3 
Protein Synonyms/Alias
  
Gene Name
 CYK3 
Gene Synonyms/Alias
 YDL117W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
288AGSFARHKYAQSFSDubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Involved in cytokinesis by recruiting INN1 to the bud neck. Cooperates with INN1 to stimulate the synthesis of the primary septum (PS) by CHS2. 
Sequence Annotation
 DOMAIN 9 70 SH3.
 MOD_RES 209 209 Phosphoserine.
 MOD_RES 292 292 Phosphoserine.
 MOD_RES 313 313 Phosphoserine.
 MOD_RES 354 354 Phosphoserine.  
Keyword
 Cell cycle; Cell division; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 885 AA 
Protein Sequence
MATNLTSLKP PFKVKARYGW SGQTKGDLGF LEGDIMEVTR IAGSWFYGKL LRNKKCSGYF 60
PHNFVILLEE RLNSSTENGR QPSKIVESFE KSNKVVIPPV PSRYSDERPR PKKKLSSSMP 120
NSPKKPVDSL TKARKAKSKE MVNEKNIYNT QSSRHHNNSA PNLPLASHSK PQVRNFEESM 180
NNPLPPLPPL PDLDNMRKTD KRAPKKSYSA NDLHMARSSR EYNYYKDNQK FYDGFIPEKR 240
YSLEEDSISS GLFSNSQYLN DSACSSENSF ALMSDFSATS AGSFARHKYA QSFSDSLQRS 300
QNANGCSTKI NDSQEFGDSN ASSRNGKMGD ILRKIIIPKR NTNIYSSSVS SPKSPKAYPK 360
LPDIQNLNLS ATPDEARDWI AVKCHLNRAR TLTKYDKHPR YMRALEENRD LILHPQDSIY 420
NGLNTNEVKG NTKPGLVDVE LAELNIEYID KMTWKRCIRD GTMTLDSWAQ TTFSARYSTV 480
LEKLRGIYIF CTEMFALTDD NGTSDFSAEP QNLEKILYRK HCTPYELTWL FKKLANSLGI 540
TCEIVIGFLK TPSAINWEFK YNHCWLRILV NKEWRFIDVI LGNVTNPIHE FVNNRKIKKA 600
ENSYFLMAPL EMIYTHIPPR EFEQHIVPSI DQLSALYLPL VFPSFFKNEL KLYKFSTALS 660
FLEDSEIYEC SLEIPNDVEV FASVVIPTDN EEASSAYRNM ELALTQIKKQ KAESGRRIAL 720
IKAVLPPNVN KGSLYIHSGV RGTQTSIANI HPLSMMVPLT HKGSNMKYEF VIKIPSESIQ 780
KIELYIVEPQ SRYLFVGNEY SFEVIQSPSD GIVYSSDEGP NQNRKQPMAI KSPSGRVHEL 840
VKSDPHFPYG TWKGSIKIKE PGVWSALVIA DSGIGWSVFA EWLCV 885 
Gene Ontology
 GO:0000142; C:cellular bud neck contractile ring; IDA:SGD.
 GO:0044697; C:HICS complex; IPI:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0000917; P:barrier septum assembly; IPI:SGD. 
Interpro
 IPR001452; SH3_domain.
 IPR002931; Transglutaminase-like. 
Pfam
  
SMART
 SM00326; SH3
 SM00460; TGc 
PROSITE
 PS50002; SH3 
PRINTS