| Tag | Content |
|---|
| CPLM ID | CPLM-021899 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Eukaryotic translation initiation factor 3 subunit A |
Protein Synonyms/Alias | eIF3a; Eukaryotic translation initiation factor 3 large subunit; Eukaryotic translation initiation factor 3 subunit 10; eIF-3-theta; p114 |
Gene Name | TIF3A1 |
Gene Synonyms/Alias | At4g11420; F25E4.40 |
Created Date | July 27, 2013 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
NCBI Taxa ID | 3702 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 61 | LDLCVDLKRGRFAKD | ubiquitination | [1] |
|
Reference | [1] Multidimensional protein identification technology (MudPIT) analysis of ubiquitinated proteins in plants. Maor R, Jones A, Nühse TS, Studholme DJ, Peck SC, Shirasu K. Mol Cell Proteomics. 2007 Apr;6(4):601-10. [ PMID: 17272265] |
Functional Description | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity). |
Sequence Annotation | DOMAIN 373 510 PCI.
CROSSLNK 61 61 Glycyl lysine isopeptide (Lys-Gly) |
Keyword | Coiled coil; Complete proteome; Cytoplasm; Initiation factor; Isopeptide bond; Protein biosynthesis; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 987 AA |
Protein Sequence | MANFAKPENA LKRADELINV GQKQDALQAL HDLITSKRYR AWQKPLEKIM FKYLDLCVDL 60
KRGRFAKDGL IQYRIVCQQV NVSSLEEVIK HFLHLATDKA EQARSQADAL EEALDVDDLE 120
ADRKPEDLQL SIVSGEKGKD RSDRELVTPW FKFLWETYRT VLEILRNNSK LEALYAMTAH 180
KAFQFCKQYK RTTEFRRLCE IIRNHLANLN KYRDQRDRPD LSAPESLQLY LDTRFDQLKV 240
ATELGLWQEA FRSVEDIYGL MCMVKKTPKS SLLMVYYSKL TEIFWISSSH LYHAYAWFKL 300
FSLQKNFNKN LSQKDLQLIA SSVVLAALSI PPFDRAQSAS HMELENEKER NLRMANLIGF 360
NLEPKFEGKD MLSRSALLSE LVSKGVLSCA SQEVKDLFHV LEHEFHPLDL GSKIQPLLEK 420
ISKSGGKLSS APSLPEVQLS QYVPSLEKLA TLRLLQQVSK IYQTIRIESL SQLVPFFQFS 480
EVEKISVDAV KNNFVAMKVD HMKGVVIFGN LGIESDGLRD HLAVFAESLS KVRAMLYPVP 540
SKASKLAGVI PNLADTVEKE HKRLLARKSI IEKRKEDQER QQLEMEREEE QKRLKLQKLT 600
EEAEQKRLAA ELAERRKQRI LREIEEKELE EAQALLEETE KRMKKGKKKP LLDGEKVTKQ 660
SVKERALTEQ LKERQEMEKK LQKLAKTMDY LERAKREEAA PLIEAAYQRR LVEEREFYER 720
EQQREVELSK ERHESDLKEK NRLSRMLGNK EIFQAQVISR RQAEFDRIRT EREERISKII 780
REKKQERDIK RKQIYYLKIE EERIRKLQEE EEARKQEEAE RLKKVEAERK ANLDKAFEKQ 840
RQREIELEEK SRREREELLR GTNAPPARLA EPTVTPVGTT APAAAAAAAG APAAPYVPKW 900
KRQTTEVSGP SAPTSSETDR RSNRGPPPGD DHWGSNRGAA QNTDRWTSNR ERSGPPAEGG 960
DRWGSGPRGS DDRRSTFGSS RPRPTQR 987 |
Gene Ontology | GO:0005829; C:cytosol; IDA:TAIR. GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP. GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP. GO:0005852; C:eukaryotic translation initiation factor 3 complex; ISS:TAIR. GO:0005886; C:plasma membrane; IDA:TAIR. GO:0003743; F:translation initiation factor activity; ISS:TAIR. GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP. GO:0006446; P:regulation of translational initiation; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |