CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029687
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Heterochromatin protein 1-binding protein 3 
Protein Synonyms/Alias
  
Gene Name
 HP1BP3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
17EKEKKVKKTIPSWATubiquitination[1, 2, 3]
35SQLARAQKQTPMASSubiquitination[2]
56AILTEAIKACFQKSGubiquitination[2]
61AIKACFQKSGASVVAubiquitination[2, 3]
90ERRGYLLKQALKRELubiquitination[2]
117VDPEPQVKLEDVLPLubiquitination[2, 3]
133FTRLCEPKEASYSLIubiquitination[2, 3]
142ASYSLIRKYVSQYYPubiquitination[2]
150YVSQYYPKLRVDIRPubiquitination[1, 2, 3]
161DIRPQLLKNALQRAVubiquitination[2, 3]
179QLEQITGKGASGTFQubiquitination[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 253 AA 
Protein Sequence
KKDEKDQSKE KEKKVKKTIP SWATLSASQL ARAQKQTPMA SSPRPKMDAI LTEAIKACFQ 60
KSGASVVAIR KYIIHKYPSL ELERRGYLLK QALKRELNRG VIKQNRSSAV DPEPQVKLED 120
VLPLAFTRLC EPKEASYSLI RKYVSQYYPK LRVDIRPQLL KNALQRAVER GQLEQITGKG 180
ASGTFQLKKS GEKPLLGGSL MEYAILSAIA AMNEPKTCST TALKKYVLEN HPGTNSNYQM 240
HLLKKTLQKC EKN 253 
Gene Ontology
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 
Interpro
 IPR005818; Histone_H1/H5.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00538; Linker_histone 
SMART
 SM00526; H15 
PROSITE
 PS51504; H15 
PRINTS