CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045689
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Purity of essence, isoform B 
Protein Synonyms/Alias
  
Gene Name
 poe 
Gene Synonyms/Alias
 Dmel_CG14472 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
27NRTGALNKNEVVNLLacetylation[1]
3947TSFEELSKIVQKVKAacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 5322 AA 
Protein Sequence
MSAHSGGTDW NSVVKALILN RTGALNKNEV VNLLKAITRC EHDFFEEESN FTQFYTAFAA 60
LAADKLMQIK TICQTQICQL HDATAVLIRF IIYRLPRVSV YETKWLLGAL KMLCEGRECP 120
ASASSSMFDY NAVANVLKSC KHPESTTKSI MPSSSSSGSG ASNDKESPKS EIKRSRSDLS 180
SVILQQLIAP LEPGKMTWVP LSEEVTDCTE QILAANVEYF QEQNGVDTLL DVCVSLPILN 240
RYRSKYMETI NGGKSLYLPL TQVEATAVKS SMNHMLTDLT ILSQAQALIE MQPLTPSRIE 300
RLSMCGIAAL YNAVLTSIAT SVLGMSQASS SQKQTASTSQ GSGVGGSSGG QSNKDHDDFE 360
DQACSIVNKA LEIYSNIGHM FKTSARIHVY QNHLCYGSWL LISGIQGAMG ASGSGGSSSD 420
SASKSASKAT KSGSEAGTAP TTPIARVNLF KVQQGFGELN AAIANHSIKL LSELIEDLKV 480
EAACGQSLES TELPEPAQFD ILQNYSSLER IVRVLNTATL HQLFTFLATV AYRKACTLKR 540
ASAKDRTECE PISYSDSTTY FNDSLSCSDN SEEDDSESYL GHWFKETLSP ETHDDNANTS 600
TQERAEQKSA LVPKLDEPHE YLDLAADIFC FLDQFLANRH AYMQRYVKAG VSDQQMLLMA 660
NIIKDFDRDV MRNESDQGSG NAPAASAGAG TSAGASTKWQ TSMIRFSGAA GRYIHNLIST 720
SLLSEQLQSN LLQHLSISPW STDTNTWPLQ VYPSTLSVLV QILLLKPTQE KEAACLSVWH 780
RLINTLVEGV CSSNTASDSD YEDLNIEHAQ LLLFLFHSLN LMQKKSILLL TAGGVIRCAE 840
VCRGISEDRP VKNSQIMLLS RLLLFLEYLM KHLYNAPPEL LDQVRWNLFS VSSMPDTQKI 900
TDLLNCRTKL NSYCRHDIEE NFRKSAGEYG SSIRPTFYSL VMGDPEISYW AQEFKLDGLA 960
WNFILCTPDK LKYPLLVDAL TDILSITDMS MYSKEKDKEA SMHNLCAIQY CFTIAWKLNL 1020
GLPPSTSHVE SLKAERSPNL HSLMWSIRLP LASSHYLVVS SLIKQGMYTQ YAETLWTHVG 1080
DIGADIKYSL KQTILGVEAF NSQMNGNGTP RLSDLILFDS LVAHMQAVAW ANKEGLKWPR 1140
KESEDAAGEQ SAGTSLTSSS NDPELYSSNE SIDDQKLKQD DDGKLSSDLQ KYNQLVNELM 1200
VKLMNSYQLL SVIVRGQMLK QLSSSTPEKA LNLIVPIVSD KPAIMLELHA AFLKLLPNED 1260
KQLIANEWPK CLMVNDFAFN GKQHPVEPYI LNVIDAHIIE LTRGSNYSTL HTLKHCLKSI 1320
LQLFELLLPH RTANAEVETQ LKQLLISSML DMRTDYLQGH SEHCLREILS GLTQEAQKLL 1380
LYEHMVGYCY RMLKEFAADL RQPQSAGPSG GAPLDQDRAM FNESMLFAVL KTMFKMLEKP 1440
VAVQAMRQFF KDQRSGSLTT LLLSFTGTSL PVSYARKMLQ FVNRLFQLSL QADSQFQHED 1500
LVECFSELAT VDVARLKQWL GHIIYGPNVS TDVSTSEALD TTCRMLTSIL QPSSSSSSNA 1560
QTPTNMATVS AMPSISDQLD PMEIEYDCGT AAGGGESNPG TGGAAANTSQ ILSLWQAAQP 1620
NPSEESSQAC DHSDSERNGA LLLSFVKSLV KDQSKASQIA PPLFQALLQL GQTLISPPQE 1680
GCDFADVLQI MITLADASPA RGHVALFNTT LLWLELAKLQ LPDKHLKHAE NVSAQLRYLS 1740
ELLQSIGFRG SRQHNPPWDD ELQTDIDELY DELAEEGEQD SLLDDSDEDT LNNKLCTFSQ 1800
TQKEFMNQHW YHCHTCNMIN TVGVCSVCAR VCHKGHDVSY AKYGNFFCDC GAKEDGSCQA 1860
LSRRIGSNEV RDSAGIGSYL PSHMSLLAGK KRSSLPVGQP VLTRKDSLTN ERIAVLTKLL 1920
EPYRETLQHQ DQWLLVVRCI LEYFDLLLPS INENCMLYSI VGCHKRATAA LERLHLLEQS 1980
FQVTDQLMFA TLGSQEGAFE NVRMNYSGDQ GQTIKHLLSS GVVRRVAFCC LSSPHGRRQQ 2040
LAVSHEKGKV TILQLSALLK QADASKRKLT LTQLSSAPIA CTVISLAANP CNEDCLAVCG 2100
LKECHILTFS SSGSTNEHIV VNPQLENGNY IKKAVWLPGS QTLLAVVTSD YVKIYDLAVD 2160
TYSPKYYYLV AVGKIRDCTF VYQDGNYNML TFASSGYIYT QQLDQQSLAV HGDFYVTNTL 2220
ELSHQHIKDI AGHIGGGGVS IYYSHTLQLL FYSYSCGRSF FSPLTNVSEG VKGIYHLDTN 2280
SASKSASKGP LQPLVQWTEV TGHPGLVYAS MQTSNNPIIL MITPERIYLQ EIKAQSAKSR 2340
IMDVVGIRHA VAGVEKTTLL LLCEDGSLRI FSAQPEYTSF WLSPQVQPFG NQLYSSTLMA 2400
KGGGSGSTSK SKSNTASGKM TSRKASQQQK QPTAGGQPVF PIDFFEHCNM LADVEFGGND 2460
LLQIYNKQKL KTRLFSTGMF VASTRSNGFT LEVINNDPNV VIVGIRVLIG TQDVQRAPQS 2520
VTILGRTIPT PVRRARWFDI PLTREEMLQS DKLLKVVFAK APDPEHVTLL DCIEVYGKSK 2580
ELVGWPDESE DVTVPGSSAP AVSSSQASSA NFGEGFNCIT QLDRMANHLL EVMDCALHLL 2640
GSGVPASMRQ KAVKTASALL LLPTPNPVQT QARYVLATLY GTRALYHNYK DGVLLQFVNR 2700
ELQSMQPKLE KLETLREIDP EAFYRLVLMV RGIANARPQS LAKICVENNY DIVPTLMGIV 2760
LELHKVTPTL DEPVNIVKRG LCQPETIVHC LVEIMYGFAL ADPGQVGRMT KYFIDLLKHD 2820
ASVISHSAKE ALILLLSPRM KRRKVAIVTP PACSTPTPST STMQALQAAA SSAASDIIEE 2880
AAGVVVDGSV GGGGLPEPNA DAEGAAVGVG GVGQQQMLNL EAFMGGGFPR LLGLPEDADD 2940
EAIMDIAIAL SLQQHGGDAN ALQSLQQGLA NLQGIRQATA MAAAVNAAAN VSLGGSDDDE 3000
GSNVATDGST LRTSPAEPAG SGGSESGGSG VESIGGTSAR SSNFGDHANA SPPRQGSTKD 3060
DQEQPGPSGV AGSGGVAVLS AMSSSEDNEA NEDDKLSKLH DLRIAVLESI IQHLGTFDLC 3120
NGLQAIPLIQ VILMLTTDLN GNNERDQQVL HDLLTALVDY VEIGKRGAAA RMETKCPGNE 3180
VRLALLSLFG VLMGKTKSKQ TGTTSPPHQF KDNSSFVAST TANVLSKSGA FVYALEALNT 3240
LLVHWKNVLG DPYAAGGGLA SQSAQASGGA SGPGVQLLKP IKHGPKPDIS ILIPHNYLKN 3300
YPDIFESYDG LLTEIIVRLP YQILRLSSAH PDNYDSGFCE AMTFTLCEYM MLNLNTLLRR 3360
QVRKLLMYIC GSKEKFRMYR DGHSLDAHFR VVKRVCNIVS SKTGAPYNAN PPMLSYDALV 3420
ELTEHLRTCQ EISQMRTGNW QKFCVVHEDA LAMLMEIACY QLDDGVSPII IQLLQAAVCN 3480
LPPPSGSKQA QPQPSTSSAS GKLRTDREKS EDTDAYYSKF DPAQCGTFVH QIFRYACDAL 3540
IIRFVRIFLL ENNITQLRWQ AHSFMTGLFE HANERQREKL LNIFWNLWPL VPTYGRRTAQ 3600
FVDLLGYLTL STRSITERLP EFVSRAVDVL RQQNELLCKH PNAPIYTTLE SILQVNGYYL 3660
ESEPCLVCNN PEVPMANIKL PSVKSDSKYT TTTMIYKLVQ CHTISKLIVR IADLKRTKMV 3720
RTINVYYNNR SVQAVVELKN RPALWHKARS VSLQSAQTEL KIDFPLPITA CNLMIEFADF 3780
FETVSGSSEN LQCPRCSAAV PAYPGVCGNC GENVFQCHKC RAINYDEKDP FLCHSCGFCK 3840
YAKFDFSMYA RVCCAVDPIE SAEDRVKTVS LIHSSLERAD RNYRQLLTNK QMLELLIQKV 3900
AEHRSSDRMV EDNMASVHST SQVNKIIQLL AQKYCVESRT SFEELSKIVQ KVKACRSELV 3960
AYDRQQQDQP PVNPGSTTGA ENPTTNRCYG CALASTEQCL TLLRAMAYNY DCRVCLYSQG 4020
LVSELAEHNL RRGTPLIQEE VRNLLVVLTK DNAEACMHLL QLVTTRVKNA LMGSIPLISL 4080
EAAVHQEMTL LEVLLGQDDI CWEYKLKVIF ELFISNCRLP RGPVTAVLHP CLRIMQNLIC 4140
PVLPGSKPNQ KVATTDLCSM KMFEGNTVDY RAWLNSDRNH EYAAWSKRMP SNNQAKLKNA 4200
KDQNVAASGG SDAPPKSRRE VRVAFLSEKY GKRWRERVLD KQRVIKPLVF NAKWIQPLLF 4260
NANSRFGRQL ACSLLSSLSR TNERRQQALN MLTSFLKHVG EAGEASAEYL MLYKNMATEQ 4320
PWLQYLVLKG VLSQISQLLA IEISKVHRME EYSLSSDLSL GYALRQYVEL LWLLLECPNI 4380
RRTYKTRMLG PVLESYLALR SLVVQRTRLI DDAQEKLLEM LEDMTSGTEE ETRAFMEILI 4440
DTVEKTRMND IKTPVFVFER LYSIIHPEEH DESEFYMTLE KDPQQEDFLQ GRMLGNPYPS 4500
SEMGLGPLMR DVKNKICTDC ELIALLEDDN GMELLVNNKI ISLDLPVKDV YKKVWLAEGG 4560
DRDAMRIVYR MRGLLGDATE EFVETLNNKS QEQVDTEQLY RMANVLADCN GLRVMLERIG 4620
SLQRISRNRE LIQVLLKLFL ICVKVRRCQE VLCQPEIGAI NTLLKVLQMC LQSENDSIQS 4680
AVTEQLLEIM ETILSKAASD TLDSFLQFSL TFGGPEYVSA LISCTDCPNV RNNPSVLRHL 4740
IRVLAALVYG NEVKMALLCE HFKDTLNFNR FDNERTPEEE FKLELFCVLT NQIEHNCIGG 4800
TLKDYIVSLG IVERSLAYIT EHAPCVKPTL LRTDSDELKE FISRPSLKYI LRFLTGLSNH 4860
HEATQVAISK DIIPIIHRLE QVSSDEHVGS LAENLLEALS TDSATAARVQ QVRDFTRAEK 4920
KRLAMATREK QLDALGMRTN EKGQVTAKGS ILQKIEKLRD ETGLTCFICR EGYACQPDKV 4980
LGIYTFTKRC NVEEFELKSR KTIGYTTVTH FNVVHVDCHT SAIRLTRGRD EWERASLQNA 5040
NTRCNGLLPL WGPAVGEAAF SACMTRHSSY MQESTQRCDI SYTSSVHDLK LLLVRFAWER 5100
SFHDDAGGGG PQSNMHFVPY LLFYSVYLLL SSRSAARDSK TLLTYLQAPP SEKWLECGYE 5160
VDGPLFMATI SLSLHSRELW NKHKLAHLKR MIAVAQGRHV SPAVLCKALL APADRQVKDY 5220
TVYKPFLMMW ALVDLIYDNL FKTVSTPKEE DWPISLFDYL RKNDEALLKS TDSILQTLTE 5280
EFLPCTSFVE FCDVAGLLHL IEHPDNFIEE ILAALPSTSS SN 5322 
Gene Ontology
 GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
 GO:0016567; P:protein ubiquitination; IEA:GOC. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS