CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009018
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative carboxymethylenebutenolidase 
Protein Synonyms/Alias
 Dienelactone hydrolase; DLH 
Gene Name
 ysgA 
Gene Synonyms/Alias
 b3830; JW5853 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
164AAHNPQLKAAVAWYGacetylation[1]
172AAVAWYGKLTGDKSLacetylation[1, 2]
177YGKLTGDKSLNSPKQacetylation[1]
225ALRAANAKAEIIVYPacetylation[1]
263QRMLEWFKQYGGKKSacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111
Functional Description
  
Sequence Annotation
 ACT_SITE 147 147 By similarity.
 ACT_SITE 204 204 By similarity.
 ACT_SITE 236 236 By similarity.  
Keyword
 Complete proteome; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 271 AA 
Protein Sequence
MATTQQSGFA PAASPLASTI VQTPDDAIVA GFTSIPSQGD NMPAYHARPK QSDGPLPVVI 60
VVQEIFGVHE HIRDICRRLA LEGYLAIAPE LYFREGDPND FADIPTLLSG LVAKVPDSQV 120
LADLDHVASW ASRNGGDVHR LMITGFCWGG RITWLYAAHN PQLKAAVAWY GKLTGDKSLN 180
SPKQPVDIAT DLNAPILGLY GGQDNSIPQE SVETMRQALR AANAKAEIIV YPDAGHAFNA 240
DYRPSYHAAS AEDGWQRMLE WFKQYGGKKS L 271 
Gene Ontology
 GO:0008806; F:carboxymethylenebutenolidase activity; IEA:EC. 
Interpro
 IPR002925; Dienelactn_hydro. 
Pfam
 PF01738; DLH 
SMART
  
PROSITE
  
PRINTS