CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030881
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transient receptor potential cation channel subfamily M member 4 
Protein Synonyms/Alias
 cDNA FLJ61284, highly similar to Homo sapiens transient receptor potential cation channel, subfamily M, member 4 (TRPM4), mRNA 
Gene Name
 TRPM4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
133ASHSAGTKAPALKGGubiquitination[1]
138GTKAPALKGGAAELRubiquitination[1]
705GNSDLYWKAQRYRLIubiquitination[1, 2]
775LTWESVHKENFLLARubiquitination[2]
806QKVDLALKQLGHIREubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Receptor; Reference proteome; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 860 AA 
Protein Sequence
MLTRIENATQ AQLPCLLVAG SGGAADCLAE TLEDTLAPGS GGARQGEARD RIRRFFPKGD 60
LEVLQAQSFH LEASLMDALL NDRPEFVRLL ISHGLSLGHF LTPMRLAQLY SAAPSNSLIR 120
NLLDQASHSA GTKAPALKGG AAELRPPDVG HVLRMLLGKM CAPRYPSGGA WDPHPGQGFG 180
ESMYLLSDKA TSPLSLDAGL GQAPWSDLLL WALLLNRAQM AMYFWEMGSN AVSSALGACL 240
LLRVMARLEP DAEEAARRKD LAFKFEGMGV DLFGECYRSS EVRAARLLLR RCPLWGDATC 300
LQLAMQADAR AFFAQDGVQS LLTQKWWGDM ASTTPIWALV LAFFCPPLIY TRLITFRKSE 360
EEPTREELEF DMDSVINGEG PVGTADPAEK TPLGVPRQSG RPGCCGGRCG GRRCLRRWFH 420
FWGAPVTIFM GNVVSYLLFL LLFSRVLLVD FQPAPPGSLE LLLYFWAFTL LCEELRQGLS 480
GGGGSLASGG PGPGHASLSQ RLRLYLADSW NQCDLVALTC FLLGVGCRLT PGLYHLGRTV 540
LCIDFMVFTV RLLHIFTVNK QLGPKIVIVS KMMKDVFFFL FFLGVWLVAY GVATEGLLRP 600
RDSDFPSILR RVFYRPYLQI FGQIPQEDMD VALMEHSNCS SEPGFWAHPP GAQAGTCVSQ 660
YANWLVVLLL VIFLLVANIL LVNLLIAMFS YTFGKVQGNS DLYWKAQRYR LIREFHSRPA 720
LAPPFIVISH LRLLLRQLCR RPRSPQPSSP ALEHFRVYLS KEAERKLLTW ESVHKENFLL 780
ARARDKRESD SERLKRTSQK VDLALKQLGH IREYEQRLKV LEREVQQCSR VLGWVAEALS 840
RSALLPPGGP PPPDLPGSKD 860 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005216; F:ion channel activity; IEA:InterPro. 
Interpro
 IPR005821; Ion_trans_dom. 
Pfam
 PF00520; Ion_trans 
SMART
  
PROSITE
  
PRINTS